Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | GPR3 | P46089 | 1/20 | 0.39 |
| ▸ | LPL | P06858 | 1/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.38 |
| ▸ | TACR2 | P21452 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SHBG | P04278 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2251999 | 1.00 | SIGMAR1 (0.40) | SIGMAR1BCHEGPR3LPLLIPG | |
| SCHEMBL2253863 | 1.00 | SIGMAR1 (0.40) | SIGMAR1BCHEGPR3LPLLIPG | |
| SCHEMBL2256254 | 1.00 | SIGMAR1 (0.40) | SIGMAR1BCHEGPR3LPLLIPG | |
| SCHEMBL5745654 | 1.00 | SIGMAR1 (0.40) | SIGMAR1BCHEGPR3LPLLIPG | |
| SCHEMBL2257127 | 1.00 | SIGMAR1 (0.40) | SIGMAR1BCHEGPR3LPLLIPG | |
| SCHEMBL2256224 | 0.94 | SIGMAR1 (0.42) | SIGMAR1BCHEHDAC1 | |
| SCHEMBL2254826 | 0.94 | SIGMAR1 (0.42) | SIGMAR1BCHEHDAC1 | |
| SCHEMBL5746343 | 0.88 | GPR3 (0.42) | GPR3LPLLIPGESR1ADRA2A | |
| SCHEMBL2253757 | 0.88 | GPR3 (0.42) | GPR3LPLLIPGESR1ADRA2A | |
| SCHEMBL2252129 | 0.88 | GPR3 (0.42) | GPR3LPLLIPGESR1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |