Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5750031 | 0.89 | OPRM1 (0.31) | OPRM1 | |
| SCHEMBL5749911 | 0.83 | HTR1A (0.32) | OPRM1 | |
| SCHEMBL5749910 | 0.83 | OPRM1 (0.31) | OPRM1 | |
| SCHEMBL5750591 | 0.83 | OPRM1 (0.32) | OPRM1 | |
| SCHEMBL5750075 | 0.81 | IRAK4 (0.32) | — | |
| SCHEMBL5750366 | 0.80 | — | — | |
| SCHEMBL5749947 | 0.78 | SSTR4 (0.32) | OPRM1 | |
| SCHEMBL5746008 | 0.75 | KDM4E (0.30) | — | |
| SCHEMBL5748603 | 0.71 | POLB (0.41) | — | |
| SCHEMBL5748387 | 0.69 | POLB (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1419155-B1 | PIPERIDINE DERIVATIVES AS ANTIBACTERIAL AGENTS | SMITHKLINE BEECHAM PLC (GB) | 2006-11-08 | — | — | EP | disclosed |