Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | LPL | P06858 | 2/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5749596 | 1.00 | KDM4E (0.36) | KDM4EALDH1A1MAPTHPGDLPL | |
| SCHEMBL5747295 | 1.00 | KDM4E (0.36) | KDM4EALDH1A1MAPTHPGDLPL | |
| SCHEMBL5750823 | 0.95 | KDM4E (0.37) | KDM4EALDH1A1MAPTHPGDTRPV1 | |
| SCHEMBL5750843 | 0.91 | ALDH1A1 (0.39) | KDM4EALDH1A1MAPTHPGDRIOK2 | |
| SCHEMBL5748108 | 0.86 | RIOK2 (0.44) | KDM4EALDH1A1MAPTHPGDRIOK2 | |
| SCHEMBL5749407 | 0.85 | TRPV1 (0.39) | KDM4ELPLLIPGTRPV1KCNH2 | |
| SCHEMBL5746412 | 0.85 | TRPV1 (0.39) | KDM4ELPLLIPGTRPV1KCNH2 | |
| SCHEMBL5745759 | 0.85 | TRPV1 (0.39) | KDM4ELPLLIPGTRPV1KCNH2 | |
| SCHEMBL5750867 | 0.85 | TRPV1 (0.41) | KDM4EALDH1A1MAPTHPGDLPL | |
| SCHEMBL5775211 | 0.83 | MAPK10 (0.38) | KDM4EMAPTLPLLIPGTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |