Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | RORA | P35398 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | RORB | Q92753 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5775211 | 0.91 | MAPK10 (0.38) | TRPV1MAPK10MAPTKDM4EMAPK8 | |
| SCHEMBL5769845 | 0.91 | MAPK10 (0.38) | TRPV1MAPK10MAPTKDM4EMAPK8 | |
| SCHEMBL5774799 | 0.91 | MAPK10 (0.38) | TRPV1MAPK10MAPTKDM4EMAPK8 | |
| SCHEMBL5776450 | 0.85 | MAPK10 (0.40) | TRPV1MAPK10MAPTKMT2AKDM4E | |
| SCHEMBL5747295 | 0.85 | KDM4E (0.36) | TRPV1MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL5748751 | 0.85 | KDM4E (0.36) | TRPV1MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL5749596 | 0.85 | KDM4E (0.36) | TRPV1MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL5914010 | 0.84 | MAPT (0.43) | TRPV1MAPTKDM4EL3MBTL1RORA | |
| SCHEMBL5779245 | 0.84 | MAPT (0.43) | TRPV1MAPTKDM4EL3MBTL1RORA | |
| SCHEMBL5775624 | 0.84 | MAPT (0.43) | TRPV1MAPTKDM4EL3MBTL1RORA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |