Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.38 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5748377 | 0.89 | CA1 (0.47) | CA1CA2CYP19A1IMPDH2IMPDH1 | |
| SCHEMBL24252 | 0.77 | CYP2A6 (0.41) | CA1CA2CYP2A6TSHRKDM4E | |
| SCHEMBL2761110 | 0.76 | CA1 (0.57) | CA1CA2CYP19A1IMPDH2IMPDH1 | |
| SCHEMBL9804912 | 0.76 | CA1 (0.57) | CA1CA2CYP19A1IMPDH2IMPDH1 | |
| SCHEMBL16875675 | 0.76 | CA1 (0.57) | CA1CA2CYP19A1IMPDH2IMPDH1 | |
| SCHEMBL31264204 | 0.76 | CA1 (0.57) | CA1CA2CYP19A1IMPDH2IMPDH1 | |
| SCHEMBL29826085 | 0.76 | CA1 (0.57) | CA1CA2CYP19A1IMPDH2IMPDH1 | |
| SCHEMBL4947557 | 0.76 | IMPDH2 (0.39) | CA1CA2CYP19A1IMPDH2IMPDH1 | |
| SCHEMBL645489 | 0.76 | CA1 (0.44) | CA1CA2CYP19A1IMPDH2IMPDH1 | |
| SCHEMBL28076506 | 0.75 | ALDH1A1 (0.39) | CA1CA2CYP2A6TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |