Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.59 |
| ▸ | CA2 | P00918 | 2/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.42 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | ITK | Q08881 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5747405 | 0.89 | CA1 (0.54) | CA1CA2SLC6A4CYP1A1CYP1A2 | |
| SCHEMBL1344052 | 0.81 | CA1 (0.67) | CA1CA2SLC6A4CYP1A1CYP1A2 | |
| SCHEMBL12320895 | 0.79 | CA1 (0.65) | CA1CA2SLC6A4CYP1A1CYP1A2 | |
| SCHEMBL12310187 | 0.79 | CA1 (0.65) | CA1CA2SLC6A4CYP1A1CYP1A2 | |
| SCHEMBL29368234 | 0.78 | HTR2A (0.54) | CYP1A2CYP1B1KDM4EALDH1A1GAA | |
| SCHEMBL1264430 | 0.78 | HTR2A (0.54) | CYP1A2CYP1B1KDM4EALDH1A1GAA | |
| SCHEMBL4083551 | 0.78 | CA1 (0.53) | CA1CA2SLC6A4CYP1A2ADORA2A | |
| SCHEMBL9747008 | 0.78 | CA1 (0.44) | CA1CA2SLC6A4KDM4EALDH1A1 | |
| SCHEMBL12320897 | 0.76 | CA1 (0.56) | CA1CA2SLC6A4CYP1A1CYP1A2 | |
| SCHEMBL17742243 | 0.76 | ALDH1A1 (0.61) | CA1CA2CYP1A2ADORA2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |