Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.39 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | NCEH1 | Q6PIU2 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | CDC7 | O00311 | 4/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13037656 | 0.81 | CA2 (0.55) | CA1CA2IMPDH2IMPDH1CYP2A6 | |
| SCHEMBL12310183 | 0.79 | CA2 (0.53) | CA1CA2IMPDH2IMPDH1CYP2A6 | |
| SCHEMBL12320904 | 0.79 | CA2 (0.53) | CA1CA2IMPDH2IMPDH1CYP2A6 | |
| SCHEMBL5748854 | 0.78 | CA1 (0.59) | CA1CA2IMPDH2IMPDH1CYP2A6 | |
| SCHEMBL12317665 | 0.77 | CA1 (0.52) | CA1CA2IMPDH2IMPDH1CYP2A6 | |
| SCHEMBL4083551 | 0.77 | CA1 (0.53) | CA1CA2IMPDH2IMPDH1CYP2A6 | |
| SCHEMBL28174467 | 0.75 | CA1 (0.50) | CA1CA2IMPDH2IMPDH1CYP2A6 | |
| SCHEMBL12317667 | 0.75 | CA1 (0.50) | CA1CA2IMPDH2IMPDH1CYP2A6 | |
| SCHEMBL9747251 | 0.75 | VCAM1 (0.43) | CA1CA2NCEH1 | |
| SCHEMBL5747405 | 0.74 | CA1 (0.54) | CA1CA2KDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511152-A2 | Quinoxaline compounds, their preparation and use | NOVO NORDISK A/S (DK) | 1992-10-28 | — | — | EP | disclosed |