Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.48 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | IMPDH2 | P12268 | 3/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.33 |
| ▸ | IMPDH1 | P20839 | 2/20 | 0.33 |
| ▸ | PDE9A | O76083 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | APAF1 | O14727 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | STAT3 | P40763 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3530070 | 0.83 | KDM4E (0.42) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL150623 | 0.79 | ALDH1A1 (0.64) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL29429129 | 0.79 | ALDH1A1 (0.64) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL10774580 | 0.73 | ALDH1A1 (0.42) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL2546104 | 0.71 | ALDH1A1 (0.59) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL148856 | 0.71 | ALDH1A1 (0.59) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL6759020 | 0.71 | CYP2A6 (0.33) | ALDH1A1TSHR | |
| SCHEMBL16213053 | 0.70 | TSHR (0.57) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL5746118 | 0.69 | ALDH1A1 (0.43) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL24617849 | 0.68 | ALDH1A1 (0.52) | ALDH1A1KDM4EMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |