Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.41 |
| ▸ | IMPDH2 | P12268 | 3/20 | 0.36 |
| ▸ | IMPDH1 | P20839 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.31 |
| ▸ | ANPEP | P15144 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7306217 | 0.76 | AR (0.36) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL7308483 | 0.76 | MAP2K1 (0.34) | ALDH1A1KDM4ECA1CA2TSHR | |
| SCHEMBL5748883 | 0.73 | ALDH1A1 (0.50) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL250481 | 0.72 | IMPDH2 (0.40) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL4940405 | 0.68 | IMPDH2 (0.40) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL3530070 | 0.67 | KDM4E (0.42) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL644339 | 0.67 | CA1 (0.40) | ALDH1A1KDM4EMAPTGAAIMPDH2 | |
| SCHEMBL578709 | 0.67 | CYP2A6 (0.32) | ALDH1A1TSHRTDP1 | |
| SCHEMBL29429129 | 0.66 | ALDH1A1 (0.64) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL150623 | 0.66 | ALDH1A1 (0.64) | ALDH1A1KDM4EMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4650838-A | OXIDATIVE, MECHANICAL AND THERMAL STABILITY | ALLIED CORPORATION (US) | 1987-03-17 | — | — | US | disclosed |
| US-4650839-A | SELF-CROSSLINKING, OXIDATION AND HEAT RESISTANCE | ALLIED CORPORATION (US) | 1987-03-17 | — | — | US | disclosed |