⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13130776 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL1703551 | 0.98 | POLB (0.33) | — | |
| SCHEMBL23829629 | 0.86 | — | — | |
| SCHEMBL860465 | 0.86 | — | — | |
| SCHEMBL50356 | 0.86 | — | — | |
| Ammonia Solution, Strong SCHEMBL15875941 | 0.84 | — | — | |
| SCHEMBL931732 | 0.82 | — | — | |
| SCHEMBL1703547 | 0.80 | — | — | |
| SCHEMBL6217231 | 0.80 | — | — | |
| Proline SCHEMBL28033434 | 0.73 | DPP4 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 169 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120158468-A | Construction method and application of escherichia coli engineering strain for improving yield of L-lysine by using ethylene glycol | 元素驱动(杭州)生物科技有限公司 | 2025-06-17 | — | — | CN | claimed |
| US-12173330-B2 | Method for producing hydroxy-L-pipecolic acid | API CORPORATION (JP) | 2024-12-24 | — | — | US | claimed |
| US-20230265475-A1 | METHOD FOR PRODUCING HYDROXY-L-PIPECOLIC ACID | API CORPORATION (JP) | 2023-08-24 | — | — | US | claimed |
| CN-116396991-A | Process for producing hydroxy-L-pipecolic acid | 株式会社API | 2023-07-07 | — | — | CN | claimed |
| US-11591577-B2 | Method for producing hydroxy-L-pipecolic acid | API CORPORATION (JP) | 2023-02-28 | — | — | US | claimed |
| CN-107532185-B | Process for producing hydroxy-L-pipecolic acid | 株式会社API | 2023-01-06 | — | — | CN | claimed |
| US-20210180097-A1 | METHOD FOR PRODUCING HYDROXY-L-PIPECOLIC ACID | API CORPORATION (JP) | 2021-06-17 | — | — | US | claimed |
| US-10954539-B2 | Method for producing hydroxy-L-pipecolic acid | API CORPORATION (JP) | 2021-03-23 | — | — | US | claimed |
| CN-111485008-A | Biological preparation method of cis-5-hydroxy-L-hexahydropicolinic acid | 日本迈科洛生物制药有限公司 | 2020-08-04 | — | — | CN | claimed |
| WO-2020139974-A1 | GLYCOGEN-NULL METHANOTROPHS AND USES THEREOF | CALYSTA, INC. (US) | 2020-07-02 | — | — | WO | claimed |
| US-20180273993-A1 | METHOD FOR PRODUCING HYDROXY-L-PIPECOLIC ACID | API CORPORATION (JP) | 2018-09-27 | — | — | US | claimed |
| EP-3358016-A1 | METHOD FOR PRODUCING HYDROXY-L-PIPECOLIC ACID | API Corporation (JP) | 2018-08-08 | — | — | EP | claimed |
| CN-107532185-A | Process for producing hydroxy-L-pipecolic acid | 株式会社API | 2018-01-02 | — | — | CN | claimed |
| EP-2601209-A1 | GENOMICS OF ACTINOPLANES UTAHENSIS | Bayer Intellectual Property GmbH (DE) | 2013-06-12 | — | — | EP | claimed |
| WO-2012016960-A1 | GENOMICS OF ACTINOPLANES UTAHENSIS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-02-09 | — | — | WO | claimed |
| WO-2026099341-A1 | BIOCONTAINMENT OF UNWANTED ENGINEERED CELLS USING NON-NATURAL AMINO ACIDS | SNIPR BIOME APS (DK) | 2026-05-15 | — | — | WO | disclosed |
| CN-120192267-A | Combined detection kit for pipecolic acid and 6-oxo-pipecolic acid, detection method and application thereof | 济南市妇幼保健院 | 2025-06-24 | — | — | CN | disclosed |
| US-5179085-A | Cerebrovascular disorders | WARNER-LAMBERT COMPANY (US) | 1993-01-12 | — | — | US | disclosed |
| EP-0421436-A2 | Substituted carboxytetrahydroisoquinolines and derivatives thereof having pharmaceutical activity | WARNER-LAMBERT COMPANY (US) | 1991-04-10 | — | — | EP | disclosed |
| US-4746653-A | ANTAGONISTS OF N-METHYL-D-ASPARTATE SENSITIVE EXCITATORY AMINO ACID RECEPTOR; TREATMENT OF MUSCULAR SPASMS, CONVULSIVE DISORDERS AND ANXIETY | CIBA-GEIGY CORPORATION (US) | 1988-05-24 | — | — | US | disclosed |