⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19925753 | 0.86 | — | — | |
| SCHEMBL4022345 | 0.82 | — | — | |
| SCHEMBL931732 | 0.80 | — | — | |
| SCHEMBL13130776 | 0.80 | — | — | |
| SCHEMBL574892 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL1703551 | 0.78 | POLB (0.33) | — | |
| SCHEMBL1703547 | 0.78 | — | — | |
| SCHEMBL6060229 | 0.74 | SMN1; SMN2 (0.32) | — | |
| SCHEMBL17675561 | 0.70 | MAPK1 (0.34) | — | |
| SCHEMBL8580876 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1176146-B1 | CARBAMOYL TETRAHYDROPYRIDINE DERIVATIVES | TAISHO PHARMACEUTICAL CO LTD (JP) | 2005-06-08 | — | — | EP | claimed |
| CN-1174984-C | Carbamoyl tetrahydropyridine derivatives | ������ҩ��ʽ���� | 2004-11-10 | — | — | CN | claimed |
| US-20030191122-A1 | Carbamoyl tetrahydropyridine derivatives | NAKAZATO ATSURO (JP) | 2003-10-09 | — | — | US | claimed |
| US-6600038-B1 | Intermediates for the preparation thereof are provided. The derivatives described above are effective for diseases which are believed to involve CRF. involving Corticotropin Releasing Factor (CRF), such as depression, anxiety, | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2003-07-29 | — | — | US | claimed |
| CN-1350536-A | Carbamoyl tetrahydropyridine derivatives | TAISHO PHARMACEUTICAL CO LTD (JP) | 2002-05-22 | — | — | CN | claimed |
| EP-1176146-A1 | CARBAMOYL TETRAHYDROPYRIDINE DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2002-01-30 | — | — | EP | claimed |
| EP-2467398-B1 | TRPC4 INHIBITORS AND USES THEREOF | POSEIDA THERAPEUTICS INC (US) | 2019-10-09 | — | — | EP | disclosed |
| EP-3194362-A1 | METHOD FOR PRODUCING 1,5-PENTANEDIISOCYANATE IN THE GAS PHASE | Covestro Deutschland AG (DE) | 2017-07-26 | — | — | EP | disclosed |
| WO-2016042125-A1 | METHOD FOR PRODUCING 1,5-PENTANEDIISOCYANATE IN THE GAS PHASE | COVESTRO DEUTSCHLAND AG (DE) | 2016-03-24 | — | — | WO | disclosed |
| US-20120148604-A1 | TRP INHIBITORS AND USES THEREOF | TRANSPOSAGEN BIOPHARMACEUTICALS, INC. (US) | 2012-06-14 | — | — | US | disclosed |
| EP-1176146-B1 | CARBAMOYL TETRAHYDROPYRIDINE DERIVATIVES | TAISHO PHARMACEUTICAL CO LTD (JP) | 2005-06-08 | — | — | EP | disclosed |
| EP-1176146-B1 | CARBAMOYL TETRAHYDROPYRIDINE DERIVATIVES | TAISHO PHARMACEUTICAL CO LTD (JP) | 2005-06-08 | — | — | EP | disclosed |
| US-6894168-B2 | Carbamoyl tetrahydropyridine derivatives | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2005-05-17 | — | — | US | disclosed |
| CN-1350536-A | Carbamoyl tetrahydropyridine derivatives | TAISHO PHARMACEUTICAL CO LTD (JP) | 2002-05-22 | — | — | CN | disclosed |
| EP-1176146-A1 | CARBAMOYL TETRAHYDROPYRIDINE DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2002-01-30 | — | — | EP | disclosed |
| EP-1176146-A1 | CARBAMOYL TETRAHYDROPYRIDINE DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2002-01-30 | — | — | EP | disclosed |
| JP-2001151777-A | DERIVATIVE OF CARBAMOYL TETRAHYDROPYRIDINE | TAISHO PHARMACEUT CO LTD | 2001-06-05 | — | — | JP | disclosed |
| WO-2000053604-A1 | CARBAMOYL TETRAHYDROPYRIDINE DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2000-09-14 | — | — | WO | disclosed |
| US-5525600-A | COMPOUND USEFUL AS ANTIPSYCHOTIC, ANTIDEPRESSANT AND ANXIBLYTIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-06-11 | — | — | US | disclosed |
| US-4785009-A | TETRAHYDROPYRIDINYL AMIDES | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1988-11-15 | — | — | US | disclosed |