SCHEMBL5748993

SCHEMBL5748993

Nc1cc2ccc3cccc4ccc(c1C=O)c2c34

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.46
ERBB2 P04626 1/20 0.46
FYN P06241 1/20 0.46
MAOA P21397 1/20 0.46
ACHE P22303 1/20 0.46
AHR P35869 1/20 0.46
ALDH1A1 P00352 5/20 0.40
HPGD P15428 5/20 0.40
HSD17B10 Q99714 4/20 0.40
CYP3A4 P08684 2/20 0.40
TSHR P16473 2/20 0.40
TDP1 Q9NUW8 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
CYP1A1 P04798 2/20 0.38
CYP1B1 Q16678 2/20 0.38
KMT2A Q03164 3/20 0.38
MEN1 O00255 2/20 0.38
THRB P10828 1/20 0.36
ERN1 O75460 3/20 0.36
KDM4E B2RXH2 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL548370 0.81 CYP1A2 (0.47) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL22159811 0.79 ERN1 (0.51) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL8003744 0.79 CYP1A2 (0.46) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL11120697 0.79 CYP1A2 (0.46) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL14639413 0.79 ALDH1A1 (0.53) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL3711459 0.79 CYP1A2 (0.46) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL9098913 0.78 MAOA (0.45) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL548054 0.77 ALDH1A1 (0.48) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL28219485 0.77 ALDH1A1 (0.54) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL5747710 0.76 CYP1A2 (0.46) CYP1A2ERBB2FYNMAOAACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2596124-B1 NOVEL SUBSTRATES THE FLUORESCENCE OF WHICH IS SUPPRESSED, PREPARATION THEREOF, AND USE THEREOF FOR IDENTIFYING, DETECTING, AND ASSAYING LEGIONELLA PNEUMOPHILIA PHARMALEADS (FR) 2015-07-08 EP claimed
US-20060293503-A1 Polyaminopyridines and method for producing same SUMITOMO SEIKA CHEMICALS CO., LTD (JP) 2006-12-28 US disclosed
EP-1669390-A1 POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 2006-06-14 EP disclosed