Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.33 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1229740 | 0.84 | KDM4E (0.43) | KDM4EALDH1A1GAAKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL8169298 | 0.82 | KDM4E (0.42) | KDM4EALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL3785573 | 0.76 | LCK (0.44) | KDM4EALDH1A1MAPTSMN1; SMN2HSD17B10 | |
| SCHEMBL4670596 | 0.76 | LCK (0.36) | KDM4EALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL5749003 | 0.72 | KDM4E (0.59) | KDM4EALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL1941944 | 0.72 | ALDH1A1 (0.40) | KDM4EALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL2253523 | 0.72 | ALDH1A1 (0.40) | KDM4EALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL29498815 | 0.71 | KDM4E (1.00) | KDM4EALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL30181949 | 0.71 | KDM4E (1.00) | KDM4EALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL29100415 | 0.71 | KDM4E (1.00) | KDM4EALDH1A1GAAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |