Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 17/20 | 0.58 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.44 |
| ▸ | PARP3 | Q9Y6F1 | 2/20 | 0.44 |
| ▸ | PLK4 | O00444 | 1/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | CSF1R | P07333 | 1/20 | 0.42 |
| ▸ | RET | P07949 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | LTK | P29376 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.42 |
| ▸ | PRKX | P51817 | 1/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.42 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8487622 | 0.84 | ALDH1A1 (0.47) | PARP1KDM4EALDH1A1 | |
| SCHEMBL16289662 | 0.79 | KDM4E (0.46) | PARP1KDM4EALDH1A1GAA | |
| SCHEMBL29923839 | 0.74 | PARP1 (1.00) | PARP1GAA | |
| SCHEMBL422282 | 0.74 | PARP1 (1.00) | PARP1GAA | |
| SCHEMBL29959688 | 0.73 | PARP1 (1.00) | PARP1PLK4MAP4K4FLT3KDM4E | |
| SCHEMBL460456 | 0.73 | PARP1 (1.00) | PARP1PLK4MAP4K4FLT3KDM4E | |
| SCHEMBL29923346 | 0.73 | PARP1 (1.00) | PARP1PLK4MAP4K4FLT3KDM4E | |
| SCHEMBL5749771 | 0.72 | KDM4E (0.42) | PARP1PLK4CHEK1AURKADAPK3 | |
| Hydrochloric Acid SCHEMBL18094592 | 0.71 | PARP1 (0.96) | PARP1PLK4MAP4K4FLT3KDM4E | |
| Hydrochloric Acid SCHEMBL29933479 | 0.71 | PARP1 (0.96) | PARP1PLK4MAP4K4FLT3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |