Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 9/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.33 |
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12883927 | 0.83 | HSD11B1 (0.41) | MEN1ALDH1A1TSHRKMT2AHSD11B1 | |
| SCHEMBL6080385 | 0.79 | HSD11B1 (0.39) | MEN1ALDH1A1TSHRKMT2AHSD11B1 | |
| SCHEMBL6078871 | 0.79 | HSD11B1 (0.39) | MEN1ALDH1A1TSHRKMT2AHSD11B1 | |
| SCHEMBL31679498 | 0.79 | HSD11B1 (0.56) | HSD11B1CYP2C9EPHX1CTSKCA1 | |
| SCHEMBL208362 | 0.75 | HSD11B1 (0.40) | MEN1ALDH1A1TSHRKMT2AHSD11B1 | |
| SCHEMBL30750664 | 0.74 | HSD11B1 (0.41) | MEN1ALDH1A1TSHRKMT2AHSD11B1 | |
| SCHEMBL8266320 | 0.73 | USP30 (0.40) | MEN1ALDH1A1TSHRKMT2AHSD11B1 | |
| SCHEMBL31425429 | 0.71 | SMN1; SMN2 (0.51) | MEN1ALDH1A1KMT2AEPHX1CTSK | |
| SCHEMBL5746419 | 0.70 | GAA (0.34) | ALDH1A1TSHR | |
| SCHEMBL18850098 | 0.70 | HSD11B1 (0.50) | HSD11B1CYP2C9EPHX1CTSKCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1578743-A4 | ANTIBACTERIAL AGENTS | GLAXO GROUP LTD (GB) | 2006-11-29 | — | — | EP | disclosed |
| EP-1578743-A2 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2005-09-28 | — | — | EP | disclosed |
| WO-2004058144-A2 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2004-07-15 | — | — | WO | disclosed |