SCHEMBL57492

SCHEMBL57492

Cc1ccc(C)c(C)c1.N=C=O.N=C=O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 5/20 0.42
ALDH1A1 P00352 3/20 0.42
TP53 P04637 1/20 0.42
RAPGEF4 Q8WZA2 2/20 0.39
NPC1 O15118 2/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
CYP1A2 P05177 2/20 0.38
CYP2A6 P11509 2/20 0.38
HSD17B10 Q99714 1/20 0.38
TSHR P16473 1/20 0.37
PRSS1 P07477 1/20 0.37
PRSS2 P07478 1/20 0.37
PRSS3 P35030 1/20 0.37
LMNA P02545 1/20 0.37
GAA P10253 2/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
MAPT P10636 2/20 0.36
RAB9A P51151 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28484247 1.00 TDP1 (0.42) TDP1ALDH1A1TP53RAPGEF4NPC1
SCHEMBL29365203 0.84
SCHEMBL1135726 0.84 TDP1 (0.55) TDP1ALDH1A1TP53RAPGEF4NPC1
SCHEMBL19744496 0.84 TDP1 (0.55) TDP1ALDH1A1TP53RAPGEF4NPC1
SCHEMBL60541 0.84
Formaldehyde SCHEMBL26618259 0.81 TDP1 (0.48) TDP1ALDH1A1TP53RAPGEF4NPC1
SCHEMBL8117972 0.81 TDP1 (0.52) TDP1ALDH1A1TP53RAPGEF4NPC1
Methane SCHEMBL28558734 0.81 TDP1 (0.52) TDP1ALDH1A1TP53RAPGEF4NPC1
Water SCHEMBL5175477 0.81 TDP1 (0.52) TDP1ALDH1A1TP53RAPGEF4NPC1
SCHEMBL31498554 0.81 TDP1 (0.52) TDP1ALDH1A1TP53RAPGEF4NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 261 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7105610-B2 Thin-layer-covered golf ball with improved velocity ACUSHNET COMPANY (US) 2006-09-12 US claimed
US-20040198918-A1 Thin-layer-covered golf ball with improved velocity JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2004-10-07 US claimed
US-20030114602-A1 Thin-layer-covered golf ball with improved velocity JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2003-06-19 US claimed
US-20030096915-A1 Thin-layer-covered golf ball with improved velocity JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2003-05-22 US claimed
US-6486261-B1 Thin-layer-covered golf ball with improved velocity ACUSHNET COMPANY 2002-11-26 US claimed
US-20020006837-A1 Wound golf ball having cast polyurethane cover ACUSHNET COMPANY 2002-01-17 US claimed
US-20260021352-A1 GOLF BALLS WITH INCREASED SHEAR DURABILITY ACUSHNET COMPANY (US) 2026-01-22 US disclosed
US-20250345663-A1 GOLF BALL COMPONENTS FORMED FROM HYDROXYURETHANE COMPOSITIONS ACUSHNET COMPANY (US) 2025-11-13 US disclosed
US-20250345662-A1 GOLF BALL COATINGS FORMED FROM HYDROXYURETHANE COMPOSITIONS ACUSHNET COMPANY (US) 2025-11-13 US disclosed
US-20250303236-A1 HIGH HARDNESS GRADIENT GOLF BALL CORES AND METHODS OF MAKING SAME ACUSHNET COMPANY (US) 2025-10-02 US disclosed
US-12427381-B2 Golf balls with increased shear durability ACUSHNET COMPANY (US) 2025-09-30 US disclosed
US-12377320-B2 Golf ball components formed from hydroxyurethane compositions ACUSHNET COMPANY (US) 2025-08-05 US disclosed
US-12370412-B2 Golf ball coatings formed from hydroxyurethane compositions ACUSHNET COMPANY (US) 2025-07-29 US disclosed
US-20030114602-A1 Thin-layer-covered golf ball with improved velocity JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2003-06-19 US disclosed
US-20030096915-A1 Thin-layer-covered golf ball with improved velocity JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2003-05-22 US disclosed
US-6562909-B2 The invention relates to a golf ball having a core and two or more cover layers. The outer cover layer includes a thin castable material and the inner cover layer a polyisoprene based material. ACUSHNET COMPANY 2003-05-13 US disclosed
US-20030083156-A1 Method of making filler-impregnated golf ball core ACUSHNET COMPANY 2003-05-01 US disclosed
US-6486261-B1 Thin-layer-covered golf ball with improved velocity ACUSHNET COMPANY 2002-11-26 US disclosed
US-20020016224-A1 Filler-impregnated golf ball core blend ACUSHNET COMPANY 2002-02-07 US disclosed
US-20020013184-A1 Golf ball with multi-layer cover ACUSHNET COMPANY 2002-01-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260021352-A1 GOLF BALLS WITH INCREASED SHEAR DURABILITY EEF2, EEF1A2, GIGYF2 TDP1 2681/4885ALDH1A1 1721/4885TP53 4172/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.