EEF2 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL1895651	1.00	2/20
Hydrochloric Acid (SCHEMBL232267)	0.97	2/20
Fluoride Ion (SCHEMBL1897318)	0.97	2/20
Hydrochloric Acid (SCHEMBL4362495)	0.97	2/20
Hydrochloric Acid (SCHEMBL4365302)	0.97	2/20
Hydrochloric Acid (SCHEMBL4366988)	0.97	2/20
SCHEMBL5283289	0.73	2/20
SCHEMBL5282345	0.71	2/20
SCHEMBL5282469	0.71	2/20
SCHEMBL5282563	0.71	2/20
SCHEMBL5283160	0.71	2/20
SCHEMBL5283462	0.71	2/20
SCHEMBL5283778	0.71	2/20
SCHEMBL3457638	0.70	2/20
SCHEMBL5282240	0.67	2/20
SCHEMBL5283917	0.67	2/20
SCHEMBL1898619	0.66	2/20
SCHEMBL2781362	0.66	2/20
SCHEMBL3309543	0.66	2/20
SCHEMBL4057502	0.66	2/20

Clinical trials — most relevant to EEF2 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Strategies to Reduce Organic Muscle Atrophy in the Intensive Care Unit	PHASE2/PHASE3	WITHDRAWN
Cardioprotective Empagliflozin for Cancer Patients Receiving Doxorubicin	PHASE2/PHASE3	UNKNOWN
Everolimus for Children With Recurrent or Progressive Ependymoma	PHASE2	COMPLETED
Study of Decitabine in Combination With Sequential Rapamycin or Ribavirin in High Risk AML Patients	PHASE1/PHASE2	COMPLETED
Antiviral Activity and Safety of 3 Different Doses of Mifepristone in Hepatitis C Infected Patients	PHASE2	COMPLETED
Tianasen (ASO-GNAO1) for GNAO1-Encephalopathy With Epilepsy and Movement Disorders.	PHASE1/PHASE2	RECRUITING
Sirolimus Treatment in Patients With Autosomal Dominant Polycystic Kidney Disease: Renal Efficacy and Safety	PHASE2	COMPLETED
ISIS 183750 With Irinotecan for Advanced Solid Tumors or Colorectal Cancer	PHASE1/PHASE2	COMPLETED
Temsirolimus and Sorafenib in Advanced Hepatocellular Carcinoma	PHASE1	COMPLETED
Phase I Study of Novel Estrogen Receptor(ER) a36 Modifier Icaritin in Advanced Breast Cancer Patients	PHASE1	UNKNOWN
Endolymphatic Sac Tumors in a Population of Patients With Von Hippel-Lindau Disease:The Natural History and Pathobiology, and a Prospective Non-Randomized Clinical Trial of Hearing Preservation Surgery in Patients With Early Stage Endolymphatic Sac Tumors	nan	COMPLETED
Effect of Branched Chain Amino Acids on Muscle	nan	COMPLETED
Quantification of GADD34 Expression in RA	nan	COMPLETED
MEHMO Natural History and Biomarkers	nan	RECRUITING
Rapamycin as a Means of Interference With Reconsolidation of Posttraumatic Stress Disorder-related Traumatic Memory	nan	COMPLETED
Autophagy in Systemic Lupus Erythematosus	nan	UNKNOWN
Regulation of Lymphocyte Anti-tumor Response in Metastatic Patients Treated With the mTOR Inhibitor Everolimus	nan	COMPLETED
Impact of Mutations in Aminoacyl tRNA Synthetases on Protein Translation and Cellular Stress	nan	WITHDRAWN
Pilot Trial of Sirolimus/MEC in High Risk Acute Myelogenous Leukemia (AML)	nan	COMPLETED
Protein Intake and Step Reduction in Older Adults	nan	COMPLETED
Transcriptomic Profile of Patients Treated With Different Modalities of Spinal Cord Stimulation	nan	UNKNOWN
EXtremely Early-onset Type 1 Diabetes EXtremely Early-onset Type 1 Diabetes (A Musketeers' Memorandum Study)	nan	RECRUITING
Intermittent Fasting for Pancreatitis	nan	NOT_YET_RECRUITING
Research on the Early and Prognosis Diagnosis of Vascular Dementia	nan	RECRUITING
Maximizing Mechanisms of Muscle Hypertrophy to Combat Sarcopenia in Older Adults	nan	COMPLETED
TranspulmonarY Estrogen Gradient and Estrogen Receptors (TYEGER) in PAH	nan	WITHDRAWN
Muscle Regrowth During Physical Rehabilitation and Amino Acid Supplementation	nan	COMPLETED
Effect of Adenovirus E1A Oncogene on DNA Replication Dynamics	nan	UNKNOWN
Evaluation of the Predictive Effect of Inflammatory Markers in MI Patients	nan	UNKNOWN
Nutraceutical Composition Containing Natural Products Derivatives on the Modulation of the Endocrine Neuroimmune Axis	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a EEF2 binder may also engage these)

Protein	Name	Similarity
P09445	—	1.000	P09445 →
Q5R8Z3	—	1.000	Q5R8Z3 →
P55823	—	1.000	P55823 →
P05197	—	1.000	P05197 →
P58252	—	1.000	P58252 →
Q3SYU2	—	1.000	Q3SYU2 →
A0SXL6	—	1.000	A0SXL6 →
Q90705	—	1.000	Q90705 →
Q1HPK6	—	1.000	Q1HPK6 →
Q9ASR1	—	1.000	Q9ASR1 →
Q6P3J5	—	1.000	Q6P3J5 →
Q754C8	—	1.000	Q754C8 →
Q23716	—	1.000	Q23716 →
P13060	—	1.000	P13060 →
O23755	—	1.000	O23755 →
Q6CPQ9	—	1.000	Q6CPQ9 →
Q875S0	—	1.000	Q875S0 →
Q6FYA7	—	1.000	Q6FYA7 →
P32324	—	1.000	P32324 →
P28996	—	1.000	P28996 →
P29691	—	1.000	P29691 →
Q874B9	—	1.000	Q874B9 →
Q06193	—	1.000	Q06193 →
C4YJQ8	—	1.000	C4YJQ8 →
Q7ZXP8	—	1.000	Q7ZXP8 →
O14460	—	1.000	O14460 →
Q5A0M4	—	1.000	Q5A0M4 →
A5DI11	—	1.000	A5DI11 →
Q17152	—	1.000	Q17152 →
Q875Z2	—	1.000	Q875Z2 →