Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | KLK7 | P49862 | 6/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CETP | P11597 | 4/20 | 0.35 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.34 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.34 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.34 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.34 |
| ▸ | KLK5 | Q9Y337 | 5/20 | 0.33 |
| ▸ | RORC | P51449 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7118804 | 0.87 | CYP3A4 (0.39) | KDM4EHSD17B10GRM4CYP3A4SMN1; SMN2 | |
| SCHEMBL6579476 | 0.85 | KCNN4 (0.40) | KDM4EKLK7KLK5RORCALDH1A1 | |
| SCHEMBL5749959 | 0.83 | KLK7 (0.38) | KDM4EKLK7CETPKLK5RORC | |
| SCHEMBL5755094 | 0.74 | CETP (0.37) | KLK7CETPKLK5ALDH1A1PRSS1 | |
| SCHEMBL5750077 | 0.71 | CETP (0.38) | CYP3A4CETP | |
| SCHEMBL5751613 | 0.70 | KCNN4 (0.39) | KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL5752174 | 0.70 | CES2 (0.37) | SMN1; SMN2RORC | |
| SCHEMBL5749040 | 0.70 | CYP3A4 (0.38) | KDM4EHSD17B10GRM4CYP3A4SMN1; SMN2 | |
| SCHEMBL7116914 | 0.69 | CES2 (0.34) | KDM4EHSD17B10SMN1; SMN2ALDH1A1 | |
| SCHEMBL5753504 | 0.67 | HCRTR1 (0.37) | KLK7CYP3A4CETPKLK5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6982348-B2 | Aminoethanol derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-01-03 | — | — | US | disclosed |
| US-20040127574-A1 | Aminoethanol derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127574-A1 | Aminoethanol derivatives | CETP, LCAT, MTTP | KDM4E 244/4885HSD17B10 151/4885KLK7 4542/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.