Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | FAAH | O00519 | 1/20 | 0.57 |
| ▸ | MGLL | Q99685 | 1/20 | 0.55 |
| ▸ | TACR3 | P29371 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.55 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.55 |
| ▸ | HTR2B | P41595 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2636547 | 0.90 | MEN1 (0.68) | MEN1KMT2AFAAHMGLLTACR3 | |
| SCHEMBL28246648 | 0.84 | MEN1 (0.52) | MEN1KMT2AFAAHTACR3 | |
| SCHEMBL1008518 | 0.84 | GRIN2D (0.59) | MEN1KMT2AFAAH | |
| SCHEMBL7238728 | 0.84 | HTT (0.70) | CYP2C9CYP2C19MAPK14HTR2BGAA | |
| SCHEMBL15718800 | 0.83 | MEN1 (0.51) | MEN1KMT2AFAAHMGLLTACR3 | |
| SCHEMBL5931753 | 0.83 | TACR3 (0.56) | MEN1KMT2AFAAHTACR3CYP2C9 | |
| SCHEMBL4959434 | 0.83 | ALDH1A1 (0.59) | MEN1KMT2AFAAHMGLLCYP2C9 | |
| SCHEMBL5169485 | 0.83 | FAAH (0.63) | FAAHCYP2C9CYP2C19MAPK14HTR2B | |
| SCHEMBL2925616 | 0.83 | MEN1 (0.60) | MEN1KMT2ACYP2C9CYP2C19MAPK14 | |
| SCHEMBL27779318 | 0.83 | MEN1 (0.51) | MEN1KMT2AFAAHCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720872-A1 | ARYL AND HETEROARYL-PIPERIDINECARBOXYLATE DERIVATIVES, THE PREPARATION AND THE USE THEREOF IN THE FORM OF FAAH ENZYME INHIBITORS | Sanofi-Aventis (FR) | 2006-11-15 | — | — | EP | disclosed |
| WO-2005090347-A1 | ARYL AND HETEROARYL-PIPERIDINECARBOXYLATE DERIVATIVES, THE PREPARATION AND THE USE THEREOF IN THE FORM OF FAAH ENZYME INHIBITORS | SANOFI-AVENTIS (FR) | 2005-09-29 | — | — | WO | disclosed |