Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 5/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CCR2 | P41597 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | CPT2 | P23786 | 1/20 | 0.40 |
| ▸ | CPT1A | P50416 | 1/20 | 0.40 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.40 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5748986 | 0.94 | PTGER4 (0.42) | PTGER4PLA2G2AP2RY14ABCB1SLC2A1 | |
| SCHEMBL6091451 | 0.92 | SLC2A1 (0.44) | PTGER4PLA2G2AP2RY14ABCB1SLC2A1 | |
| SCHEMBL6091083 | 0.92 | SMN1; SMN2 (0.44) | PTGER4PLA2G2AP2RY14ABCB1SLC2A1 | |
| SCHEMBL6093040 | 0.92 | SERPINE1 (0.45) | PLA2G2AP2RY14ABCB1SLC2A1SMN1; SMN2 | |
| SCHEMBL6091904 | 0.91 | CCR2 (0.44) | PTGER4P2RY14ABCB1SLC2A1HPGD | |
| SCHEMBL6093678 | 0.91 | TP53 (0.41) | PTGER4PLA2G2AP2RY14ABCB1SLC2A1 | |
| SCHEMBL6093252 | 0.91 | GRIN1 (0.45) | PTGER4PLA2G2AP2RY14ABCB1SLC2A1 | |
| SCHEMBL5738359 | 0.90 | ADORA3 (0.46) | PTGER4PLA2G2AP2RY14ABCB1SLC2A1 | |
| SCHEMBL5749266 | 0.90 | TP53 (0.45) | PTGER4PLA2G2AP2RY14ABCB1SLC2A1 | |
| SCHEMBL6091080 | 0.90 | HDAC1 (0.42) | PTGER4P2RY14ABCB1SLC2A1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060160879-A1 | Indoles useful in the treatment of inflammation | BIOLIPOX AB (SE) | 2006-07-20 | — | — | US | disclosed |
| EP-1646624-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2006-04-19 | — | — | EP | disclosed |
| WO-2005005415-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2005-01-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060160879-A1 | Indoles useful in the treatment of inflammation | IDO1, PTGS1, IDO2 | PTGER4 22/4885PLA2G2A 982/4885P2RY14 1414/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.