Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.53 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18431952 | 1.00 | PTGS2 (0.53) | PTGS2ESR1ESR2MAPTALDH1A1 | |
| SCHEMBL13508376 | 0.95 | PTGS2 (0.57) | PTGS2ESR1ESR2MAPTALDH1A1 | |
| SCHEMBL443217 | 0.95 | PTGS2 (0.57) | PTGS2ESR1ESR2MAPTALDH1A1 | |
| SCHEMBL139360 | 0.95 | PTGS2 (0.57) | PTGS2ESR1ESR2MAPTALDH1A1 | |
| SCHEMBL13807879 | 0.94 | PTGS2 (0.57) | PTGS2ESR1ESR2MAPTALDH1A1 | |
| SCHEMBL5754961 | 0.94 | PTGS2 (0.57) | PTGS2ESR1ESR2MAPTALDH1A1 | |
| SCHEMBL14174011 | 0.94 | ESR1 (0.58) | PTGS2ESR1ESR2MAPTALDH1A1 | |
| SCHEMBL5754966 | 0.94 | PTGS2 (0.57) | PTGS2ESR1ESR2MAPTALDH1A1 | |
| SCHEMBL7840548 | 0.92 | PTGS2 (0.56) | PTGS2ESR1ESR2MAPTALDH1A1 | |
| SCHEMBL7840546 | 0.92 | PTGS2 (0.56) | PTGS2ESR1ESR2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1137326-B1 | ORGANIC ELECTROLUMINESCENT ELEMENT | NIPPON STEEL CHEMICAL CO (JP) | 2006-07-05 | — | — | EP | disclosed |
| EP-1137326-A1 | ORGANIC ELECTROLUMINESCENT ELEMENT | Nippon Steel Chemical Co., Ltd. (JP) | 2001-09-26 | — | — | EP | disclosed |