Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.52 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.48 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29361654 | 1.00 | TDP1 (0.54) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL18311461 | 0.90 | TDP1 (0.56) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL7122584 | 0.88 | TDP1 (0.44) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL73931 | 0.82 | TDP1 (0.50) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL29888274 | 0.82 | TDP1 (0.50) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL574038 | 0.82 | TDP1 (0.50) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL825499 | 0.82 | TDP1 (0.50) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL30924883 | 0.82 | TDP1 (0.50) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL308086 | 0.80 | TDP1 (0.50) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL938956 | 0.80 | TDP1 (0.48) | TDP1ATMALDH1A1HIF1AVCAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1228 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116283661-B | 2, 3-Difluoro-6- (trifluoromethyl) -benzonitrile compound and preparation method thereof | 江苏广域化学有限公司 | 2025-05-09 | — | — | CN | claimed |
| CN-117049938-B | Preparation method of 6-bromo-2, 3-difluorotoluene | 山东轩德医药科技有限公司 | 2024-06-14 | — | — | CN | claimed |
| CN-118084632-A | Preparation and purification process of 2, 3-difluoroanisole | 江西正梦新材料有限公司 | 2024-05-28 | — | — | CN | claimed |
| CN-117049938-A | Preparation method of 6-bromo-2, 3-difluorotoluene | 山东轩德医药科技有限公司 | 2023-11-14 | — | — | CN | claimed |
| CN-116836060-A | Preparation method of 2,3, 4-trifluoro nitrobenzene | 山东京博农化科技股份有限公司 | 2023-10-03 | — | — | CN | claimed |
| CN-116553997-B | Synthesis method of intermediate 1,2, 3-trifluoro-benzene for synthesizing 3,4, 5-trifluoro-bromobenzene | 山东国邦药业有限公司 | 2023-09-26 | — | — | CN | claimed |
| CN-116553997-A | Synthesis method of intermediate 1,2, 3-trifluoro-benzene for synthesizing 3,4, 5-trifluoro-bromobenzene | 山东国邦药业有限公司 | 2023-08-08 | — | — | CN | claimed |
| CN-116283876-A | Process for preparing benzopyrone | 江苏广域化学有限公司 | 2023-06-23 | — | — | CN | claimed |
| CN-116283661-A | 2, 3-difluoro-6- (trifluoromethyl) -benzonitrile compound and preparation method thereof | 江苏广域化学有限公司 | 2023-06-23 | — | — | CN | claimed |
| CN-115804849-A | Drug delivery system of photosensitizer and nitric oxide prodrug and preparation method thereof | 河北工业大学 | 2023-03-17 | — | — | CN | claimed |
| CN-1357529-A | Prepn process of 2,3,4-trifluoro nitrobenzene | KUNSHAN SHUNGHE PHARMACEUTICAL (CN) | 2002-07-10 | — | — | CN | claimed |
| CN-1055927-C | Synthetizing and application of laevo-rotation ofloxacin analogue | SHANGHAI INST OF MEDICINES CHI (CN) | 2000-08-30 | — | — | CN | claimed |
| CN-1181381-A | Synthetizing and application of laevo-rotation ofloxacin analogue | SHANGHAI INST OF MEDICINES CHI (CN) | 1998-05-13 | — | — | CN | claimed |
| EP-0608713-B1 | 2,3-Difluoro-6-introbenzonitrile and 2-chloro-5,6-difluorobenzonitrile, process for their preparation and their use in the preparation of 2,3,6-trifluorobenzoic acid | HOECHST AG (DE) | 1996-12-27 | — | — | EP | claimed |
| US-5478963-A | 2,3-difluoro-6-nitrobenzonitrile and 2-chloro-5,6-difluorobenzonitrile-(2,3-difluoro-6-chlorobenzonitrile), process for their preparation and their use for the preparation of 2,3,6-trifluorobenzoic acid | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-12-26 | — | — | US | claimed |
| EP-0550535-B1 | PROCESS FOR PRODUCING 2,3-DIFLUOR-6-NITROPHENOL | HOECHST AG (DE) | 1995-07-19 | — | — | EP | claimed |
| EP-0608713-A1 | 2,3-Difluoro-6-introbenzonitrile and 2-chloro-5,6-difluorobenzonitrile, process for their preparation and their use in the preparation of 2,3,6-trifluorobenzoic acid | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-08-03 | — | — | EP | claimed |
| EP-0602552-A1 | 2,3,4-trifluor-N-ethylaniline and process for its preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-06-22 | — | — | EP | claimed |
| US-5292967-A | Process for producing 2,3-difluoro-6-nitrophenol | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-03-08 | — | — | US | claimed |
| EP-0165375-A2 | Derivative of pyrido-benzothiazine with high anti-microbial activity | MEDIOLANUM FARMACEUTICI s.r.l. (IT) | 1985-12-27 | — | — | EP | claimed |