SCHEMBL825499

SCHEMBL825499

O=[N+]([O-])c1ccc(F)c([N+](=O)[O-])c1F

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.50
ATM Q13315 1/20 0.50
ALDH1A1 P00352 4/20 0.48
HIF1A Q16665 2/20 0.48
VCAM1 P19320 1/20 0.46
TSHR P16473 5/20 0.45
MAPK1 P28482 1/20 0.45
CASP6 P55212 1/20 0.44
MAPT P10636 4/20 0.40
POLB P06746 2/20 0.40
GPR35 Q9HC97 1/20 0.39
CYP3A4 P08684 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
TP53 P04637 1/20 0.38
HPGD P15428 1/20 0.38
TXNRD1 Q16881 1/20 0.38
TXNRD3 Q86VQ6 1/20 0.38
TXNRD2 Q9NNW7 1/20 0.38
LMNA P02545 3/20 0.37
KDM4E B2RXH2 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30924883 1.00 TDP1 (0.50) TDP1ATMALDH1A1HIF1AVCAM1
SCHEMBL3077412 0.84 TDP1 (0.52) TDP1ATMALDH1A1HIF1AVCAM1
SCHEMBL30946522 0.84 TDP1 (0.52) TDP1ATMALDH1A1HIF1AVCAM1
SCHEMBL1340438 0.84 ALDH1A1 (0.43) TDP1ATMALDH1A1HIF1AVCAM1
SCHEMBL29860351 0.84 ALDH1A1 (0.43) TDP1ATMALDH1A1HIF1AVCAM1
SCHEMBL73931 0.83 TDP1 (0.50) TDP1ATMALDH1A1HIF1AVCAM1
SCHEMBL29361654 0.82 TDP1 (0.54) TDP1ATMALDH1A1HIF1AVCAM1
SCHEMBL57498 0.82 TDP1 (0.54) TDP1ATMALDH1A1HIF1AVCAM1
SCHEMBL18311461 0.81 TDP1 (0.56) TDP1ATMALDH1A1HIF1AVCAM1
SCHEMBL7513494 0.81 ALDH1A1 (0.48) TDP1ATMALDH1A1HIF1AVCAM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 177 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117164576-A Synthesis method of flumioxazin 上海农帆生物科技有限公司 2023-12-05 CN claimed
CN-109809508-A The preprocess method of fluorine-containing nitrophenol wastewater 利尔化学股份有限公司 2019-05-28 CN claimed
EP-1549350-A1 PHARMACEUTICALLY ACTIVE OLIGOSACCHARIDE CONJUGATES Fresenius Kabi Deutschland GmbH (DE) 2005-07-06 EP claimed
WO-2004032971-A1 PHARMACEUTICALLY ACTIVE OLIGOSACCHARIDE CONJUGATES FRESENIUS KABI DEUTSCHLAND GMBH (DE) 2004-04-22 WO claimed
US-12427172-B2 Ionizing irradiation sterilization of bacterial minicell-based biopharmaceuticals and methods of use VAXIION THERAPEUTICS, LLC (US) 2025-09-30 US disclosed
CN-116120185-B Method for preparing nitroso-containing aromatic compound from amino-containing aromatic compound 安徽省化工研究院 2025-01-28 CN disclosed
EP-4378958-A2 HIGH-AFFINITY ANTI-MERTK ANTIBODIES AND USES THEREOF Inspirna, Inc. (US) 2024-06-05 EP disclosed
CN-117904309-A Use of cholesterol or cholesterol metabolizing enzymes for identifying chemotactic dendritic cells and/or chemotactic states and functions thereof 中国人民解放军海军军医大学 2024-04-19 CN disclosed
EP-3930847-B1 HIGH-AFFINITY ANTI-MERTK ANTIBODIES AND USES THEREOF INSPIRNA INC (US) 2024-02-14 EP disclosed
CN-117321200-A Method for assessing efficacy of viral vector particles 朱诺治疗学股份有限公司 2023-12-29 CN disclosed
CN-117321417-A Method for determining the efficacy of therapeutic cell compositions 朱诺治疗学股份有限公司 2023-12-29 CN disclosed
EP-4284919-A1 METHODS OF MAKING MODIFIED TUMOR INFILTRATING LYMPHOCYTES AND THEIR USE IN ADOPTIVE CELL THERAPY Iovance Biotherapeutics, Inc. (US) 2023-12-06 EP disclosed
EP-0686043-A1 COMPOSITIONS AND METHODS OF APPLICATION OF REACTIVE ANTIVIRAL POLYMERS WANG, Jui, H. (US) 1995-12-13 EP disclosed
WO-1994025494-A1 RIGID MATERIALS HAVING HIGH SURFACE AREA AND LOW DENSITY ALLIEDSIGNAL INC. (US) 1994-11-10 WO disclosed
WO-1994019012-A2 COMPOSITIONS AND METHODS OF APPLICATION OF REACTIVE ANTIVIRAL POLYMERS WANG JUI H (US) 1994-09-01 WO disclosed
US-5328939-A Crosslinked nitrogen-containing polymers ALLIEDSIGNAL INC. (US) 1994-07-12 US disclosed
US-5322935-A Crosslinking chitosans with anionic salts followed by covalent crosslinkers; high strength, dimensional stability ALLIEDSIGNAL INC. (US) 1994-06-21 US disclosed
EP-0359063-A2 Antibody having high affinity to methamphetamine and immunogen for obtaining the same MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1990-03-21 EP disclosed
US-4704355-A ADENOSINE 5*-TRIPHOSPHATE NEW HORIZONS DIAGNOSTICS CORPORATION (US) 1987-11-03 US disclosed
US-4104126-A Non-isotopic substrate assay employing bacteriolysis products NICHOLS INSTITUTE OF ENDOCRINOLOGY, INC. (US) 1978-08-01 US disclosed