Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 5/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL938956 | 0.94 | TDP1 (0.48) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL57498 | 0.88 | TDP1 (0.54) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL29361654 | 0.88 | TDP1 (0.54) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL29705523 | 0.82 | TDP1 (0.48) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL288026 | 0.82 | TDP1 (0.48) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL7121790 | 0.80 | TSHR (0.45) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL18311461 | 0.79 | TDP1 (0.56) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL19329434 | 0.79 | ALDH1A1 (0.48) | TDP1ATMALDH1A1HIF1ATSHR | |
| SCHEMBL15347823 | 0.77 | TDP1 (0.47) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL4063467 | 0.76 | ALDH1A1 (0.50) | TDP1ATMALDH1A1HIF1ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0970100-B1 | BENZIMIDAZOLE DERIVATIVES | GLAXO GROUP LTD (GB) | 2003-11-12 | — | — | EP | disclosed |