SCHEMBL5750127

SCHEMBL5750127

NC(=O)c1ccc(C(=O)O)c2ccccc12

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.64
KMT2A Q03164 1/20 0.64
NR4A1 P22736 1/20 0.54
NR4A2 P43354 1/20 0.54
NR4A3 Q92570 1/20 0.54
ALDH1A1 P00352 4/20 0.50
WDR5 P61964 1/20 0.50
ALOX15 P16050 1/20 0.50
KDM4E B2RXH2 5/20 0.48
TSHR P16473 3/20 0.48
HSD17B10 Q99714 3/20 0.48
HPGD P15428 2/20 0.48
LDHA P00338 1/20 0.48
CYP2C9 P11712 1/20 0.48
ALOX12 P18054 1/20 0.48
ATIC P31939 1/20 0.48
GAA P10253 1/20 0.47
BCAT2 O15382 1/20 0.47
MAPT P10636 2/20 0.46
POLB P06746 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7916759 0.91 NR4A1 (0.59) ATMKMT2ANR4A1NR4A2NR4A3
SCHEMBL28639283 0.91 ATM (0.75) ATMKMT2AALDH1A1KDM4ETSHR
SCHEMBL30838412 0.88 NR4A1 (0.65) NR4A1NR4A2NR4A3ALDH1A1WDR5
SCHEMBL29406630 0.88 NR4A1 (0.65) NR4A1NR4A2NR4A3ALDH1A1WDR5
SCHEMBL28798 0.88 NR4A1 (0.65) NR4A1NR4A2NR4A3ALDH1A1WDR5
SCHEMBL30838413 0.88 NR4A1 (0.65) NR4A1NR4A2NR4A3ALDH1A1WDR5
Hydrochloric Acid SCHEMBL4429797 0.85 NR4A1 (0.62) NR4A1NR4A2NR4A3ALDH1A1WDR5
SCHEMBL31436579 0.85 NR4A1 (0.62) NR4A1NR4A2NR4A3ALDH1A1WDR5
Fluoride SCHEMBL21331927 0.85 NR4A1 (0.62) NR4A1NR4A2NR4A3ALDH1A1WDR5
Bromide SCHEMBL21173947 0.85 NR4A1 (0.62) NR4A1NR4A2NR4A3ALDH1A1WDR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2813891-B1 Photoresist underlayer film-forming composition and pattern forming process SHINETSU CHEMICAL CO (JP) 2018-01-17 EP disclosed
US-6982348-B2 Aminoethanol derivatives TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2006-01-03 US disclosed
US-20040127574-A1 Aminoethanol derivatives TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2004-07-01 US disclosed
EP-1362846-A1 AMINOETHANOL DERIVATIVES Takeda Chemical Industries, Ltd. (JP) 2003-11-19 EP disclosed
CN-1441637-A Compositions for repelling crawling insects BAYER AG (DE) 2003-09-10 CN disclosed
US-20020094993-A1 Compositions for repelling crawling insects S.C. JOHNSON & SON, INC. 2002-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040127574-A1 Aminoethanol derivatives CETP, LCAT, MTTP ATM 3113/4885KMT2A 404/4885NR4A1 595/4885
US-20020094993-A1 Compositions for repelling crawling insects ACHE, DDT, GAP43 ATM 3858/4885KMT2A 3439/4885NR4A1 4435/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.