Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KARS1 | Q15046 | 7/20 | 0.46 |
| ▸ | KDR | P35968 | 2/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.46 |
| ▸ | GSK3A | P49840 | 2/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | IGF1R | P08069 | 1/20 | 0.46 |
| ▸ | LTK | P29376 | 1/20 | 0.46 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.46 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.46 |
| ▸ | CLK2 | P49760 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | CDK7 | P50613 | 1/20 | 0.46 |
| ▸ | CDK9 | P50750 | 1/20 | 0.46 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.46 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.46 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.46 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5748170 | 0.83 | MAPK10 (0.56) | KDRMAPK8GSK3AMAP4K4ABL1 | |
| SCHEMBL5771191 | 0.81 | MAPK10 (0.51) | KARS1KDRMAPK8GSK3AMAP4K4 | |
| SCHEMBL5748905 | 0.81 | RIOK2 (0.47) | KARS1LCKIGF1RMAPK9CDK5 | |
| SCHEMBL5748311 | 0.81 | KMT2A (0.45) | KARS1KDRMAPK8GSK3AMAP4K4 | |
| SCHEMBL5748045 | 0.79 | KMT2A (0.49) | KDRIGF1RKMT2AMEN1NPC1 | |
| SCHEMBL5750225 | 0.79 | RIOK2 (0.38) | KARS1GSK3AIGF1RMAPK9GSK3B | |
| SCHEMBL18772775 | 0.78 | TNNI3K (0.59) | KARS1KDRABL1KMT2AMEN1 | |
| SCHEMBL5745780 | 0.76 | TRPV1 (0.37) | KARS1MAPK9NPC1RAB9ACASP3 | |
| SCHEMBL5751084 | 0.76 | NOS2 (0.57) | KDRMAPK8GSK3AMAP4K4ABL1 | |
| SCHEMBL5750033 | 0.76 | IGF1R (0.55) | KDRMAPK8GSK3AMAP4K4ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |