Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.41 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | PREP | P48147 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | CCR8 | P51685 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4067873 | 0.74 | KCNH2 (0.63) | NCF1KCNH2 | |
| SCHEMBL4063487 | 0.74 | KCNH2 (0.60) | NCF1ENPP1KCNH2 | |
| SCHEMBL5751789 | 0.72 | NCF1 (0.44) | NCF1ENPP1KCNH2CHRM4CCR8 | |
| SCHEMBL4066233 | 0.71 | NCF1 (0.62) | NCF1ENPP1KCNH2CHRM4MTNR1B | |
| SCHEMBL4065882 | 0.70 | NCF1 (0.52) | NCF1ENPP1PREPSLC2A1MTNR1A | |
| SCHEMBL4065991 | 0.70 | KCNH2 (0.56) | NCF1ENPP1KCNH2 | |
| SCHEMBL1223790 | 0.67 | NCF1 (0.59) | NCF1ENPP1KCNH2CHRM4MTNR1B | |
| SCHEMBL18979927 | 0.66 | NCF1 (0.53) | NCF1ENPP1KCNH2CHRM4MTNR1A | |
| SCHEMBL4068568 | 0.64 | KCNH2 (0.52) | KCNH2 | |
| SCHEMBL1223418 | 0.64 | NCF1 (0.62) | NCF1KCNH2CHRM4BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1605938-A4 | ANTIBACTERIAL AGENTS | GLAXO GROUP LTD (GB) | 2006-11-22 | — | — | EP | disclosed |
| EP-1605938-A2 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2005-12-21 | — | — | EP | disclosed |
| WO-2004087145-A2 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2004-10-14 | — | — | WO | disclosed |