Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.44 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CCR8 | P51685 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4065991 | 0.81 | KCNH2 (0.56) | NCF1ENPP1KCNH2 | |
| SCHEMBL4067873 | 0.80 | KCNH2 (0.63) | NCF1KCNH2 | |
| SCHEMBL4063487 | 0.78 | KCNH2 (0.60) | NCF1ENPP1KCNH2 | |
| SCHEMBL4066233 | 0.73 | NCF1 (0.62) | NCF1ENPP1KCNH2CHRM4KMT2A | |
| SCHEMBL4065882 | 0.73 | NCF1 (0.52) | NCF1ENPP1SIRT2SIRT1SIRT3 | |
| SCHEMBL4066813 | 0.72 | KCNH2 (0.46) | KCNH2 | |
| SCHEMBL5750709 | 0.72 | NCF1 (0.41) | NCF1ENPP1KCNH2CHRM4CCR8 | |
| SCHEMBL4064236 | 0.72 | KCNH2 (0.51) | ENPP1KCNH2 | |
| SCHEMBL2949571 | 0.72 | KCNH2 (0.51) | ENPP1KCNH2 | |
| SCHEMBL4068568 | 0.71 | KCNH2 (0.52) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1605938-A4 | ANTIBACTERIAL AGENTS | GLAXO GROUP LTD (GB) | 2006-11-22 | — | — | EP | disclosed |
| EP-1605938-A2 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2005-12-21 | — | — | EP | disclosed |
| WO-2004087145-A2 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2004-10-14 | — | — | WO | disclosed |