Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 16/20 | 0.47 |
| ▸ | HTR2A | P28223 | 4/20 | 0.45 |
| ▸ | HTR2C | P28335 | 4/20 | 0.45 |
| ▸ | HTR2B | P41595 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6222735 | 0.91 | HTR2A (0.45) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL4055816 | 0.88 | HRH2 (0.50) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL4051958 | 0.88 | HRH2 (0.51) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL4051922 | 0.87 | HRH2 (0.46) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL4053826 | 0.87 | HRH2 (0.48) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL4053376 | 0.81 | CNR1 (0.48) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL5750985 | 0.80 | HRH2 (0.53) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL4055298 | 0.79 | HRH2 (0.66) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL5748984 | 0.77 | HRH2 (0.48) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL4056351 | 0.77 | NOS2 (0.46) | HRH2HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050176751-A1 | Azaindolylpiperidine derivatives as antihistaminic and antiallergic agents | LABORATORIOS ALMIRALL, S.A. (ES) | 2005-08-11 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050176751-A1 | Azaindolylpiperidine derivatives as antihistaminic and antiallergic agents | HRH2, HRH1, HRH4 | HRH2 1/4885HTR2A 83/4885HTR2C 190/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.