Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of 1,4-Butanediol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.59 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.59 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.59 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | FNTA | P49354 | 1/20 | 0.42 |
| ▸ | FNTB | P49356 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | ARG2 | P78540 | 1/20 | 0.36 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL28326314 | 0.96 | GPR84 (0.65) | GPR84FFAR1FFAR4CAMK2ACA1 | |
| Bicarbonate SCHEMBL28191659 | 0.96 | GPR84 (0.65) | GPR84FFAR1FFAR4CAMK2ACA1 | |
| 1,5-Pentanediol SCHEMBL29150346 | 0.96 | GPR84 (0.65) | GPR84FFAR1FFAR4CAMK2ACA1 | |
| Bicarbonate SCHEMBL28380298 | 0.96 | GPR84 (0.65) | GPR84FFAR1FFAR4CAMK2ACA1 | |
| 1,6-Hexanediol SCHEMBL6707356 | 0.96 | GPR84 (0.65) | GPR84FFAR1FFAR4CAMK2ACA1 | |
| 1,5-Pentanediol SCHEMBL575113 | 0.96 | GPR84 (0.65) | GPR84FFAR1FFAR4CAMK2ACA1 | |
| 1,6-Hexanediol SCHEMBL28984424 | 0.96 | GPR84 (0.65) | GPR84FFAR1FFAR4CAMK2ACA1 | |
| 1,6-Hexanediol SCHEMBL28737103 | 0.96 | GPR84 (0.65) | GPR84FFAR1FFAR4CAMK2ACA1 | |
| 1,6-Hexanediol SCHEMBL628080 | 0.96 | GPR84 (0.65) | GPR84FFAR1FFAR4CAMK2ACA1 | |
| 1,6-Hexanediol SCHEMBL29109662 | 0.96 | GPR84 (0.65) | GPR84FFAR1FFAR4CAMK2ACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 190 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119591131-A | Preparation method of fluorophosphate | 浙江省化工研究院有限公司 | 2025-03-11 | — | — | CN | claimed |
| CN-113646169-B | 2 Component solvent-based adhesive composition | 陶氏环球技术有限责任公司 | 2024-05-24 | — | — | CN | claimed |
| CN-118022388-A | Apparatus and method for devolatilizing polymers | 浙江大学 | 2024-05-14 | — | — | CN | claimed |
| CN-113518790-B | Two-component solvent-based adhesive composition | 陶氏环球技术有限责任公司 | 2023-08-25 | — | — | CN | claimed |
| CN-113956505-B | Polylactic acid emulsion, and preparation method and application thereof | 海南赛诺实业有限公司 | 2023-05-16 | — | — | CN | claimed |
| CN-116041696-A | Multiblock copolymer based on long-chain polyamide and aliphatic polycarbonate and preparation method thereof | 中国五环工程有限公司 | 2023-05-02 | — | — | CN | claimed |
| CN-112961885-B | Method for synthesizing enzyme-catalyzed poly (1, 4-butanediol carbonate) | 源创核新(北京)新材料科技有限公司 | 2022-08-19 | — | — | CN | claimed |
| CN-112194783-B | Method for preparing high molecular weight poly (butylene glycol) carbonate by organic base and Ti/Si composite material catalysis | 中国科学院青岛生物能源与过程研究所 | 2022-04-22 | — | — | CN | claimed |
| CN-112280028-B | Method for preparing high molecular weight poly (butylene glycol) carbonate by catalyzing inorganic salt and Ti/Si composite material | 中国科学院青岛生物能源与过程研究所 | 2022-04-22 | — | — | CN | claimed |
| CN-113956428-A | Novel polyurethane material and preparation method thereof | 中国科学院山西煤炭化学研究所 | 2022-01-21 | — | — | CN | claimed |
| CN-113646169-A | 2-component solvent-based adhesive composition | 陶氏环球技术有限责任公司 | 2021-11-12 | — | — | CN | claimed |
| CN-113518790-A | Two-component solvent-based adhesive composition | 陶氏环球技术有限责任公司 | 2021-10-19 | — | — | CN | claimed |
| CN-112961885-A | Method for synthesizing enzyme catalyzed poly 1, 4-butanediol carbonate | 源创核新(北京)新材料科技有限公司 | 2021-06-15 | — | — | CN | claimed |
| CN-112280028-A | Method for preparing high molecular weight poly (butylene glycol) carbonate by catalyzing inorganic salt and Ti/Si composite material | 中国科学院青岛生物能源与过程研究所 | 2021-01-29 | — | — | CN | claimed |
| CN-112194783-A | Method for preparing high molecular weight poly (butylene glycol) carbonate by organic base and Ti/Si composite material catalysis | 中国科学院青岛生物能源与过程研究所 | 2021-01-08 | — | — | CN | claimed |
| CN-109229874-B | Preparation method of plastic packaging material for refrigeration | 湖州达立智能设备制造有限公司 | 2020-12-08 | — | — | CN | claimed |
| US-9556406-B2 | Compositions comprising benefit agent and aprotic solvent | MILLIKEN & COMPANY (US) | 2017-01-31 | — | — | US | claimed |
| US-9540601-B2 | Composition comprising benefit agent and aprotic solvent | THE PROCTER & GAMBLE COMPANY (US) | 2017-01-10 | — | — | US | claimed |
| US-4307032-A | Process for the preparation of dialkyl carbonates | BAYER AKTIENGESELLSCHAFT (DE) | 1981-12-22 | — | — | US | claimed |
| US-4083876-A | ALKYLENE CARBONATES WITH HYDROGEN SULFIDE | ERDOLCHEMIE GMBH (DT) | 1978-04-11 | — | — | US | claimed |