Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 9/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 2/20 | 0.33 |
| ▸ | DDO | Q99489 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5748318 | 1.00 | MTNR1A (0.33) | MTNR1AGABRA1GABRB2KDM4EALDH1A1 | |
| SCHEMBL2254127 | 0.85 | MTNR1A (0.37) | MTNR1AHTR2A | |
| SCHEMBL2252083 | 0.85 | MTNR1A (0.37) | MTNR1AHTR2A | |
| SCHEMBL5747955 | 0.83 | TLR8 (0.41) | MTNR1A | |
| SCHEMBL2252218 | 0.83 | TLR8 (0.41) | MTNR1A | |
| SCHEMBL2256018 | 0.83 | TLR8 (0.41) | MTNR1A | |
| SCHEMBL2252230 | 0.83 | TLR8 (0.41) | MTNR1A | |
| SCHEMBL2253485 | 0.83 | TLR8 (0.41) | MTNR1A | |
| SCHEMBL5746737 | 0.83 | TLR8 (0.41) | MTNR1A | |
| SCHEMBL498622 | 0.82 | ALDH1A1 (0.46) | MTNR1AGABRA1GABRB2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |