Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 1/20 | 0.42 |
| ▸ | MELK | Q14680 | 2/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | SUV39H2 | Q9H5I1 | 4/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4072478 | 0.83 | KCNH2 (0.42) | SUV39H2KCNH2 | |
| SCHEMBL30354542 | 0.81 | DYRK1A (0.43) | PTPN11KCNH2DYRK1A | |
| SCHEMBL4073223 | 0.80 | SUV39H2 (0.48) | MELKSUV39H2KCNH2DYRK1A | |
| SCHEMBL4068365 | 0.79 | KCNH2 (0.37) | PTPN11KCNH2DYRK1A | |
| SCHEMBL4066839 | 0.79 | CYP8B1 (0.46) | ENPP1KCNH2 | |
| SCHEMBL4071738 | 0.79 | ABCB1 (0.49) | ENPP1MELKKCNH2 | |
| SCHEMBL4074224 | 0.77 | KCNH2 (0.58) | KCNH2 | |
| SCHEMBL1224242 | 0.74 | SSTR2 (0.46) | KCNH2 | |
| SCHEMBL4063521 | 0.73 | KCNH2 (0.41) | KCNH2 | |
| SCHEMBL4067241 | 0.72 | ENPP1 (0.46) | ENPP1MELKPTPN11SUV39H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1605938-A4 | ANTIBACTERIAL AGENTS | GLAXO GROUP LTD (GB) | 2006-11-22 | — | — | EP | disclosed |
| US-20060189601-A1 | Antibacterial agents | GLAXO GROUP LIMITED (GB) | 2006-08-24 | — | — | US | disclosed |
| EP-1605938-A2 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2005-12-21 | — | — | EP | disclosed |
| WO-2004087145-A2 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2004-10-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060189601-A1 | Antibacterial agents | NQO2, NRDC, IFNG | ENPP1 577/4885MELK 1838/4885PTPN11 3552/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.