Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | GRM5 | P41594 | 2/20 | 0.35 |
| ▸ | SLC9A1 | P19634 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5780048 | 0.83 | GRM5 (0.39) | MAPTTP53PTK2BSMN1; SMN2KMT2A | |
| SCHEMBL14086451 | 0.79 | SMN1; SMN2 (0.40) | MAPTTP53PTK2BSMN1; SMN2POLB | |
| SCHEMBL5751634 | 0.79 | GRM5 (0.35) | MAPTTP53PTK2BSMN1; SMN2KMT2A | |
| SCHEMBL4718820 | 0.75 | — | — | |
| SCHEMBL5751959 | 0.73 | ACLY (0.30) | — | |
| SCHEMBL5750618 | 0.71 | HRH4 (0.35) | SMN1; SMN2KMT2AMEN1GRM5LMNA | |
| SCHEMBL4815038 | 0.69 | TSHR (0.42) | MAPTTP53SMN1; SMN2KMT2ARAB9A | |
| SCHEMBL408899 | 0.67 | GLA (0.33) | MAPTSMN1; SMN2LMNATSHRALDH1A1 | |
| SCHEMBL4718003 | 0.67 | TP53 (0.35) | TP53LMNAHTT | |
| SCHEMBL13906840 | 0.66 | GRM5 (0.36) | SMN1; SMN2POLBTDP1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060160811-A1 | Aryl-condensed 3-arylpridine compounds and use thereof for controlling pathogenic fungi | BASF AKTIENGESELLSCHAFT (DE) | 2006-07-20 | — | — | US | disclosed |
| EP-1648890-A2 | ARYL-CONDENSED 3-ARYLPYRIDINE COMPOUNDS AND USE THEREOF FOR CONTROLLING PATHOGENIC FUNGI | BASF AKTIENGESELLSCHAFT (DE) | 2006-04-26 | — | — | EP | disclosed |
| WO-2005010000-A2 | ARYL-CONDENSED 3-ARYLPYRIDINE COMPOUNDS AND USE THEREOF FOR CONTROLLING PATHOGENIC FUNGI | BASF AKTIENGESELLSCHAFT (DE) | 2005-02-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060160811-A1 | Aryl-condensed 3-arylpridine compounds and use thereof for controlling pathogenic fungi | CBR3, C1R, CBR1 | MAPT 4678/4885TP53 3430/4885PTK2B 4286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.