Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGT2B17 | O75795 | 2/20 | 0.51 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.39 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12014020 | 0.94 | UGT2B17 (0.58) | UGT2B17OPRL1KCNH2OPRM1ADRA2A | |
| SCHEMBL1746541 | 0.89 | OPRL1 (0.51) | UGT2B17OPRL1KCNH2OPRM1ADRA2A | |
| SCHEMBL1151022 | 0.89 | OPRL1 (0.51) | UGT2B17OPRL1KCNH2OPRM1ADRA2A | |
| SCHEMBL30997127 | 0.89 | OPRL1 (0.51) | UGT2B17OPRL1KCNH2OPRM1ADRA2A | |
| SCHEMBL1508536 | 0.89 | OPRL1 (0.51) | UGT2B17OPRL1KCNH2OPRM1ADRA2A | |
| SCHEMBL29325486 | 0.80 | GID4 (0.41) | UGT2B17KMT2APOLLBRD3 | |
| SCHEMBL29325214 | 0.80 | GID4 (0.41) | UGT2B17KMT2APOLLBRD3 | |
| SCHEMBL29325484 | 0.80 | HTR2C (0.41) | UGT2B17OPRL1OPRM1KMT2ATAS1R3 | |
| SCHEMBL30004585 | 0.80 | GID4 (0.41) | UGT2B17KMT2APOLLBRD3 | |
| SCHEMBL7919900 | 0.80 | GID4 (0.41) | UGT2B17KMT2APOLLBRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6982348-B2 | Aminoethanol derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-01-03 | — | — | US | disclosed |
| US-20040127574-A1 | Aminoethanol derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-07-01 | — | — | US | disclosed |
| EP-1362846-A1 | AMINOETHANOL DERIVATIVES | Takeda Chemical Industries, Ltd. (JP) | 2003-11-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127574-A1 | Aminoethanol derivatives | CETP, LCAT, MTTP | UGT2B17 1123/4885OPRL1 1125/4885KCNH2 4532/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.