Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.54 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 6/20 | 0.46 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | IAPP | P10997 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29634734 | 1.00 | NFE2L2 (0.54) | NFE2L2HAO1BACE1PTGER1PTGER4 | |
| SCHEMBL5752220 | 1.00 | NFE2L2 (0.54) | NFE2L2HAO1BACE1PTGER1PTGER4 | |
| SCHEMBL11550267 | 0.86 | NFE2L2 (0.54) | NFE2L2HAO1BACE1PTGER1PTGER4 | |
| SCHEMBL11550275 | 0.86 | NFE2L2 (0.54) | NFE2L2HAO1BACE1PTGER1PTGER4 | |
| SCHEMBL27832643 | 0.82 | IAPP (0.60) | NFE2L2BACE1PTGER1PTGER4PTGER3 | |
| SCHEMBL2476699 | 0.82 | IAPP (0.60) | NFE2L2BACE1PTGER1PTGER4PTGER3 | |
| SCHEMBL13287300 | 0.82 | IAPP (0.60) | NFE2L2BACE1PTGER1PTGER4PTGER3 | |
| SCHEMBL3362442 | 0.82 | IAPP (0.60) | NFE2L2BACE1PTGER1PTGER4PTGER3 | |
| SCHEMBL10986381 | 0.81 | NFE2L2 (0.53) | NFE2L2HAO1BACE1RAB9AALDH1A1 | |
| SCHEMBL10348522 | 0.81 | NFKB1 (0.65) | NFE2L2BACE1RAB9AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6982348-B2 | Aminoethanol derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-01-03 | — | — | US | disclosed |
| US-20040127574-A1 | Aminoethanol derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-07-01 | — | — | US | disclosed |
| EP-1362846-A1 | AMINOETHANOL DERIVATIVES | Takeda Chemical Industries, Ltd. (JP) | 2003-11-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127574-A1 | Aminoethanol derivatives | CETP, LCAT, MTTP | NFE2L2 1599/4885HAO1 2928/4885BACE1 835/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.