Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.35 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5757246 | 0.86 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL5356355 | 0.85 | GAA (0.35) | ALDH1A1SMN1; SMN2MAPTPOLBCYP2C19 | |
| SCHEMBL5344672 | 0.76 | PPARG (0.54) | EPHX1L3MBTL1PPARGPPARA | |
| SCHEMBL5352506 | 0.73 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL5356190 | 0.73 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL5349008 | 0.73 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL27479897 | 0.70 | NR1D1 (0.46) | ALDH1A1PPARGPPARAMAPTKMT2A | |
| SCHEMBL5346018 | 0.70 | CACNA1B (0.46) | EPHX1ALDH1A1L3MBTL1PPARGPPARA | |
| SCHEMBL5343462 | 0.70 | CACNA1B (0.40) | EPHX1ALDH1A1SMN1; SMN2MAPTPOLB | |
| SCHEMBL5353582 | 0.70 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2L3MBTL1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0997147-B1 | AMINO ACID DERIVATIVES | ONO PHARMACEUTICAL CO (JP) | 2006-03-15 | — | — | EP | claimed |