Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.51 |
| ▸ | WNT3A | P56704 | 3/20 | 0.51 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL351400 | 0.89 | CTNNB1 (0.64) | ALDH1A1MAPK1CTNNB1WNT3AMRGPRX4 | |
| SCHEMBL18641649 | 0.87 | CTNNB1 (0.67) | ALDH1A1MAPK1CTNNB1WNT3AMRGPRX4 | |
| SCHEMBL5503013 | 0.86 | CTNNB1 (0.49) | ALDH1A1MAPK1CTNNB1WNT3AMRGPRX4 | |
| SCHEMBL15104920 | 0.83 | TSHR (0.53) | CTNNB1WNT3ASMYD3TSHRKIF11 | |
| SCHEMBL31085181 | 0.83 | KDM4E (0.49) | ALDH1A1CTNNB1WNT3ASMYD3KDM4E | |
| SCHEMBL1907961 | 0.83 | KDM4E (0.49) | ALDH1A1CTNNB1WNT3ASMYD3KDM4E | |
| SCHEMBL3255990 | 0.81 | ALDH1A1 (0.52) | ALDH1A1MAPK1CTNNB1WNT3AMRGPRX4 | |
| SCHEMBL21674399 | 0.81 | ALDH1A1 (0.52) | ALDH1A1MAPK1CTNNB1WNT3AMRGPRX4 | |
| SCHEMBL2647988 | 0.80 | CTNNB1 (0.55) | CTNNB1WNT3ASMYD3 | |
| SCHEMBL758294 | 0.79 | KDM4E (0.47) | ALDH1A1MAPK1CTNNB1WNT3ASMYD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6982348-B2 | Aminoethanol derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-01-03 | — | — | US | disclosed |
| US-20040127574-A1 | Aminoethanol derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-07-01 | — | — | US | disclosed |
| EP-1362846-A1 | AMINOETHANOL DERIVATIVES | Takeda Chemical Industries, Ltd. (JP) | 2003-11-19 | — | — | EP | disclosed |
| WO-1996022280-A1 | N-SUBSTITUTED 1-ACYLAMINOALKYL PIPERIDINES FOR TREATMENT OF CEREBRAL DISORDERS AND DEPRESSIONS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-07-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127574-A1 | Aminoethanol derivatives | CETP, LCAT, MTTP | ALDH1A1 783/4885MAPK1 2140/4885CTNNB1 1000/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.