Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.44 |
| ▸ | WNT3A | P56704 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7153475 | 0.85 | KDM4E (0.50) | ALDH1A1TSHRRAB9ACTNNB1WNT3A | |
| SCHEMBL29746867 | 0.83 | TSHR (0.53) | ALDH1A1TSHRRAB9ACTNNB1WNT3A | |
| SCHEMBL9141299 | 0.83 | KMT2A (0.56) | ALDH1A1MAPK1TSHRRAB9ANPC1 | |
| SCHEMBL11586028 | 0.82 | ALDH1A1 (0.46) | ALDH1A1MAPK1TSHRRAB9ACTNNB1 | |
| SCHEMBL8522592 | 0.82 | RARG (0.62) | ALDH1A1RAB9ATDP1RXRANPC1 | |
| SCHEMBL8522590 | 0.82 | RARG (0.62) | ALDH1A1RAB9ATDP1RXRANPC1 | |
| SCHEMBL703172 | 0.81 | TSHR (0.45) | ALDH1A1TSHRRAB9ACTNNB1WNT3A | |
| SCHEMBL1811733 | 0.81 | RAB9A (0.49) | ALDH1A1MAPK1RAB9ATDP1ALOX5 | |
| SCHEMBL21674399 | 0.81 | ALDH1A1 (0.52) | ALDH1A1MAPK1TSHRRAB9ACTNNB1 | |
| SCHEMBL5753071 | 0.81 | ALDH1A1 (0.52) | ALDH1A1MAPK1TSHRRAB9ACTNNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12044968-B2 | Protective film-forming composition having acetal structure and amide structure | NISSAN CHEMICAL CORPORATION (JP) | 2024-07-23 | — | — | US | disclosed |
| US-12044968-B2 | Protective film-forming composition having acetal structure and amide structure | NISSAN CHEMICAL CORPORATION (JP) | 2024-07-23 | — | — | US | disclosed |
| US-20240072809-A1 | ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF EXTRACELLULAR PROTEINS | AVILAR THERAPEUTICS, INC. (US) | 2024-02-29 | — | — | US | disclosed |
| US-20240072809-A1 | ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF EXTRACELLULAR PROTEINS | AVILAR THERAPEUTICS, INC. (US) | 2024-02-29 | — | — | US | disclosed |
| US-11819551-B2 | ASGPR-binding compounds for the degradation of extracellular proteins | AVILAR THERAPEUTICS, INC. (US) | 2023-11-21 | — | — | US | disclosed |
| US-11819551-B2 | ASGPR-binding compounds for the degradation of extracellular proteins | AVILAR THERAPEUTICS, INC. (US) | 2023-11-21 | — | — | US | disclosed |
| EP-4214197-A1 | SUBSTITUTED PYRIDINE DERIVATIVES AS SARM1 INHIBITORS | Nura Bio, Inc. (US) | 2023-07-26 | — | — | EP | disclosed |
| WO-2023028338-A2 | MANNOSE 6-PHOSPHATE OR ASGPR RECEPTOR BINDING COMPOUNDS FOR THE DEGRADATION OF EXTRACELLULAR PROTEINS | AVILAR THERAPEUTICS, INC. (US) | 2023-03-02 | — | — | WO | disclosed |
| US-20220135539-A1 | BIARYL AMIDE COMPOUNDS, PREPARATION METHODS AND MEDICAL APPLICATIONS THEREOF | Eternity Bioscience Inc. | 2022-05-05 | — | — | US | disclosed |
| WO-2022060812-A1 | SUBSTITUTED PYRIDINE DERIVATIVES AS SARM1 INHIBITORS | NURA BIO, INC. (US) | 2022-03-24 | — | — | WO | disclosed |
| US-20200409260-A1 | PROTECTIVE FILM FORMING COMPOSITION HAVING AN ACETAL STRUCTURE | NISSAN CHEMICAL CORPORATION (JP) | 2020-12-31 | — | — | US | disclosed |
| US-20100137428-A1 | OXYGEN CONTAINING HETEROCYCLES AS GLYCINE TRANSPORTER INHIBITING COMPOUNDS | GLAXO GROUP LIMITED | 2010-06-03 | — | — | US | disclosed |
| EP-1833811-B1 | OXYGEN CONTAINING HETEROCYCLES AS GLYCINE TRANSPORTER INHIBITING COMPOUNDS | GLAXO GROUP LTD (GB) | 2010-06-02 | — | — | EP | disclosed |
| EP-1833811-A1 | OXYGEN CONTAINING HETEROCYCLES AS GLYCINE TRANSPORTER INHIBITING COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2007-09-19 | — | — | EP | disclosed |
| WO-2006067437-A1 | OXYGEN CONTAINING HETEROCYCLES AS GLYCINE TRANSPORTER INHIBITING COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2006-06-29 | — | — | WO | disclosed |
| US-4117228-A | ANTIHISTAMINES | EISAI CO., LTD. (JP) | 1978-09-26 | — | — | US | disclosed |
| US-4083853-A | ANTIHISTAMINES | EISAI CO., LTD. (JA) | 1978-04-11 | — | — | US | disclosed |
| US-4051125-A | ANTIHISTAMINES | EISAI CO., LTD. (JA) | 1977-09-27 | — | — | US | disclosed |
| US-4026895-A | ANTIHISTAMIC ACTIVITY | EISAI CO., LTD. (JA) | 1977-05-31 | — | — | US | disclosed |
| US-3981864-A | ANTIHISTAMINES | EISAI CO., LTD. (JA) | 1976-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11819551-B2 | ASGPR-binding compounds for the degradation of extracellular proteins | ASGR1, ENGASE, FCGR2A | ALDH1A1 3319/4885MAPK1 3337/4885TSHR 645/4885 |
| US-20220135539-A1 | BIARYL AMIDE COMPOUNDS, PREPARATION METHODS AND MEDICAL APPLICATIONS THEREOF | BRAF, NRAS, RAF1 | ALDH1A1 1618/4885MAPK1 899/4885TSHR 1552/4885 |
| US-20100137428-A1 | OXYGEN CONTAINING HETEROCYCLES AS GLYCINE TRANSPORTER INHIBITING COMPOUNDS | SLC18A2, SLC1A2, SLC6A3 | ALDH1A1 483/4885MAPK1 2553/4885TSHR 3617/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.