Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 4/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5753481 | 1.00 | ALDH1A1 (0.50) | ALDH1A1CYP2C19CYP3A4CYP2C9SMN1; SMN2 | |
| SCHEMBL28313620 | 0.82 | ALDH1A1 (0.50) | ALDH1A1CYP3A4SMN1; SMN2TAAR1NPC1 | |
| Phentermine SCHEMBL6100627 | 0.79 | TAAR1 (0.73) | ALDH1A1CYP2C19CYP3A4CYP2C9SMN1; SMN2 | |
| Phentermine SCHEMBL6100624 | 0.79 | TAAR1 (0.73) | ALDH1A1CYP2C19CYP3A4CYP2C9SMN1; SMN2 | |
| SCHEMBL27656915 | 0.78 | CAPN1 (0.39) | ALDH1A1CYP2C19CYP3A4CYP2C9TAAR1 | |
| SCHEMBL27531745 | 0.75 | GABRP (0.50) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL6667248 | 0.74 | ALDH1A1 (0.54) | ALDH1A1CYP2C19CYP3A4CYP2C9SMN1; SMN2 | |
| SCHEMBL26654265 | 0.74 | ALDH1A1 (0.54) | ALDH1A1CYP2C19CYP3A4CYP2C9SMN1; SMN2 | |
| SCHEMBL96457 | 0.74 | TAAR1 (0.52) | ALDH1A1CYP2C19CYP3A4CYP2C9SMN1; SMN2 | |
| SCHEMBL8900699 | 0.74 | SLC6A2 (0.52) | ALDH1A1CYP2C19CYP3A4CYP2C9SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6982348-B2 | Aminoethanol derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-01-03 | — | — | US | disclosed |
| US-20040127574-A1 | Aminoethanol derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-07-01 | — | — | US | disclosed |
| EP-1362846-A1 | AMINOETHANOL DERIVATIVES | Takeda Chemical Industries, Ltd. (JP) | 2003-11-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127574-A1 | Aminoethanol derivatives | CETP, LCAT, MTTP | ALDH1A1 783/4885CYP2C19 1759/4885CYP3A4 775/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.