Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KISS1R | Q969F8 | 1/20 | 0.72 |
| ▸ | PRKCA | P17252 | 14/20 | 0.72 |
| ▸ | GSK3B | P49841 | 14/20 | 0.72 |
| ▸ | PRKCB | P05771 | 13/20 | 0.72 |
| ▸ | PRKCG | P05129 | 12/20 | 0.72 |
| ▸ | PRKCD | Q05655 | 7/20 | 0.72 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.51 |
| ▸ | PRKCZ | Q05513 | 3/20 | 0.48 |
| ▸ | PRKACA | P17612 | 1/20 | 0.47 |
| ▸ | PRKACG | P22612 | 1/20 | 0.47 |
| ▸ | PRKACB | P22694 | 1/20 | 0.47 |
| ▸ | PRKCH | P24723 | 1/20 | 0.42 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.42 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.42 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5758093 | 0.87 | KISS1R (0.81) | KISS1RPRKCAGSK3BPRKCBPRKCG | |
| SCHEMBL5793514 | 0.85 | PRKCA (0.90) | KISS1RPRKCAGSK3BPRKCBPRKCG | |
| SCHEMBL5754471 | 0.85 | KISS1R (0.82) | KISS1RPRKCAGSK3BPRKCBPRKCG | |
| SCHEMBL3785953 | 0.84 | KISS1R (1.00) | KISS1RPRKCAGSK3BPRKCBPRKCG | |
| SCHEMBL3773926 | 0.84 | PRKCA (1.00) | KISS1RPRKCAGSK3BPRKCBPRKCG | |
| SCHEMBL19751910 | 0.84 | KISS1R (0.83) | KISS1RPRKCAGSK3BPRKCBPRKCG | |
| SCHEMBL5758656 | 0.83 | PRKCA (0.95) | KISS1RPRKCAGSK3BPRKCBPRKCG | |
| SCHEMBL13580118 | 0.81 | KISS1R (0.78) | KISS1RPRKCAGSK3BPRKCBPRKCG | |
| SCHEMBL27502356 | 0.79 | KISS1R (0.70) | KISS1RPRKCAGSK3BPRKCBPRKCG | |
| SCHEMBL5759736 | 0.73 | PRKCA (0.70) | KISS1RPRKCAGSK3BPRKCBPRKCG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362047-B1 | INDAZOLYL-SUBSTITUTED PYRROLINE COMPOUNDS AS KINASE INHIBITORS | ORTHO MCNEIL PHARM INC (US) | 2006-05-17 | — | — | EP | disclosed |