Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 2/20 | 0.39 |
| ▸ | CHUK | O15111 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 3/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | MELK | Q14680 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2906304 | 0.72 | IKBKB (0.36) | IKBKBCHUKFFAR4HTR1ASLC6A2 | |
| SCHEMBL2906305 | 0.72 | CHRM2 (0.39) | IKBKBCHUKFFAR4SLC6A2SLC6A4 | |
| SCHEMBL2908377 | 0.66 | LTC4S (0.42) | FFAR4CYP3A4PDE4APDE4BPDE4C | |
| SCHEMBL30350527 | 0.64 | FFAR4 (0.43) | CNR2FFAR4PDE4APDE4BPDE4C | |
| SCHEMBL2909751 | 0.64 | FFAR4 (0.43) | CNR2FFAR4PDE4APDE4BPDE4C | |
| SCHEMBL2240323 | 0.64 | CHRNB2 (0.66) | IKBKBCHUKSLC6A2SLC6A4KDM1A | |
| SCHEMBL2933257 | 0.62 | CHRM2 (0.38) | FFAR4PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4670846 | 0.62 | SLC18A3 (0.52) | CYP2D6SMN1; SMN2CHRNB4CHRNA3 | |
| SCHEMBL6606787 | 0.62 | PDE4D (0.42) | CNR2FFAR4PDE4APDE4BPDE4C | |
| SCHEMBL6606783 | 0.62 | PDE4D (0.42) | CNR2FFAR4PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1692109-A2 | PHOSPHODIESTERASE 4 INHIBITORS, INCLUDING N-SUBSTITUTED DIARYLAMINE ANALOGS | Memory Pharmaceuticals Corporation (US) | 2006-08-23 | — | — | EP | disclosed |
| WO-2005061458-A2 | PHOSPHODIESTERASE 4 INHIBITORS, INCLUDING N-SUBSTITUTED DIARYLAMINE ANALOGS | MEMORY PHARMACEUTICALS CORPORATION (US) | 2005-07-07 | — | — | WO | disclosed |