SCHEMBL5754010

SCHEMBL5754010

Cc1nc2ccc(C(c3ccc4nc(C)oc(=O)c4c3)C(c3ccc4nc(-c5ccccc5)oc(=O)c4c3)c3ccc4nc(-c5ccccc5)oc(=O)c4c3)cc2c(=O)o1

nearest known ligand 0.65

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ELANE P08246 4/20 0.55
NPC1 O15118 5/20 0.52
RAB9A P51151 4/20 0.52
ALDH1A1 P00352 7/20 0.46
HPGD P15428 4/20 0.46
F2 P00734 2/20 0.46
KMT2A Q03164 2/20 0.46
C1R P00736 1/20 0.46
KDM4E B2RXH2 4/20 0.46
MAPT P10636 3/20 0.46
SMN1; SMN2 Q16637 3/20 0.46
LMNA P02545 1/20 0.46
RXFP1 Q9HBX9 1/20 0.46
HSD17B10 Q99714 1/20 0.46
HPN P05981 1/20 0.44
TP53 P04637 3/20 0.44
MEN1 O00255 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL758384 0.80 ELANE (0.55) ELANENPC1RAB9AALDH1A1HPGD
SCHEMBL913895 0.79 NPC1 (0.70) ELANENPC1RAB9AALDH1A1HPGD
SCHEMBL12352014 0.78 ELANE (0.66) ELANENPC1RAB9AALDH1A1C1R
SCHEMBL10780103 0.77 ELANE (0.77) ELANENPC1RAB9AALDH1A1HPGD
SCHEMBL10781834 0.76 ELANE (0.74) ELANENPC1RAB9AALDH1A1HPGD
SCHEMBL2704120 0.74 C1R (0.68) ELANENPC1RAB9AALDH1A1HPGD
SCHEMBL2843939 0.74 NPC1 (0.70) ELANENPC1RAB9AALDH1A1HPGD
SCHEMBL16767209 0.74 ELANE (0.66) ELANENPC1RAB9AALDH1A1HPGD
SCHEMBL2333007 0.73 RAB9A (0.69) ELANENPC1RAB9AALDH1A1HPGD
SCHEMBL759610 0.73 ELANE (0.59) ELANEALDH1A1KMT2AKDM4ETP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1657573-A2 NEAR-INFRARED ABSORBING FILM, PROCESS FOR PRODUCING THE SAME, NEAR-INFRARED ABSORBING FILM ROLL, PROCESS FOR PRODUCING THE SAME AND NEAR-INFRARED ABSORBING FILTER TOYO BOSEKI KABUSHIKI KAISHA (JP) 2006-05-17 EP disclosed