SCHEMBL12352014

SCHEMBL12352014

Cc1nc2ccc(-c3ccccc3)cc2c(=O)o1

nearest known ligand 0.66

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ELANE P08246 8/20 0.66
GAA P10253 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.59
KCNA3 P22001 2/20 0.50
NPC1 O15118 1/20 0.48
RAB9A P51151 1/20 0.48
C1R P00736 1/20 0.45
ALDH1A1 P00352 1/20 0.44
TRIM58 Q8NG06 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4117968 0.80 ELANE (1.00) ELANENPC1RAB9AC1RALDH1A1
SCHEMBL29444197 0.79 ELANE (1.00) ELANENPC1RAB9A
SCHEMBL146072 0.79 ELANE (1.00) ELANENPC1RAB9A
SCHEMBL12352090 0.78 ELANE (1.00) ELANEGAAKCNA3NPC1RAB9A
SCHEMBL12597036 0.78 GAA (0.75) ELANEGAAL3MBTL1NPC1RAB9A
SCHEMBL5754010 0.78 ELANE (0.55) ELANENPC1RAB9AC1RALDH1A1
SCHEMBL12352004 0.77 ELANE (0.70) ELANERAB9A
SCHEMBL3539033 0.77 ELANE (0.70) ELANEKCNA3C1RALDH1A1
SCHEMBL4123057 0.77 ELANE (0.70) ELANEALDH1A1
SCHEMBL31000399 0.77 ELANE (0.70) ELANEL3MBTL1C1RALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8541488-B2 Formed resin article and polymer film FUJIFILM CORPORATION (JP) 2013-09-24 US disclosed
US-8541488-B2 Formed resin article and polymer film FUJIFILM CORPORATION (JP) 2013-09-24 US disclosed
US-20110186791-A1 ULTRAVIOLET ABSORBENT COMPOSITION FUJIFILM CORPORATION (JP) 2011-08-04 US disclosed
US-20110186791-A1 ULTRAVIOLET ABSORBENT COMPOSITION FUJIFILM CORPORATION (JP) 2011-08-04 US disclosed
US-20110092619-A1 FORMED RESIN ARTICLE AND POLYMER FILM FUJIFILM CORPORATION (JP) 2011-04-21 US disclosed
US-20110092619-A1 FORMED RESIN ARTICLE AND POLYMER FILM FUJIFILM CORPORATION (JP) 2011-04-21 US disclosed
US-7897761-B2 Heterocyclic compound FUJIFILM CORPORATION (JP) 2011-03-01 US disclosed
US-7897761-B2 Heterocyclic compound FUJIFILM CORPORATION (JP) 2011-03-01 US disclosed
US-20110024701-A1 Ultraviolet Absorbent Composition FUJIFILM CORPORATION (JP) 2011-02-03 US disclosed
US-20110024701-A1 Ultraviolet Absorbent Composition FUJIFILM CORPORATION (JP) 2011-02-03 US disclosed
EP-2270076-A1 RESIN MOLDED PRODUCT AND POLYMER FILM FUJIFILM Corporation (JP) 2011-01-05 EP disclosed
EP-2270113-A1 ULTRAVIOLET ABSORBENT COMPOSITIONS FUJIFILM Corporation (JP) 2011-01-05 EP disclosed
US-20100004439-A1 Heterocyclic Compound FUJIFLM CORPORATION (JP) 2010-01-07 US disclosed
US-20100004439-A1 Heterocyclic Compound FUJIFLM CORPORATION (JP) 2010-01-07 US disclosed
US-20090239982-A1 Ultraviolet Absorbent and Heterocyclic Compound FUJIFILM CORPORATION (JP) 2009-09-24 US disclosed
US-20090239982-A1 Ultraviolet Absorbent and Heterocyclic Compound FUJIFILM CORPORATION (JP) 2009-09-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090239982-A1 Ultraviolet Absorbent and Heterocyclic Compound CYP2A6, CYP2B6, XPO6 ELANE 1479/4885GAA 2950/4885L3MBTL1 2124/4885
US-20100004439-A1 Heterocyclic Compound PTGER1, CYP1A1, ALOX12 ELANE 1343/4885GAA 4088/4885L3MBTL1 4235/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.