SCHEMBL5754263

SCHEMBL5754263

Nc1cccc(N)c1-c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.55
HSD17B10 Q99714 4/20 0.55
CYP3A4 P08684 5/20 0.50
ALOX15 P16050 1/20 0.50
CASP1 P29466 1/20 0.50
CASP7 P55210 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
MAOA P21397 1/20 0.46
TDP1 Q9NUW8 2/20 0.46
TAAR1 Q96RJ0 2/20 0.46
LMNA P02545 1/20 0.46
MAPT P10636 1/20 0.46
HTT P42858 1/20 0.46
PTPRC P08575 1/20 0.44
ADORA2A P29274 1/20 0.44
TSHR P16473 3/20 0.43
HPGD P15428 2/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
HSPA1A P0DMV8 1/20 0.42
PABPC1 P11940 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24254918 0.88 CYP3A4 (0.47) ALDH1A1HSD17B10CYP3A4ALOX15CASP1
SCHEMBL25014 0.85 HSD17B10 (0.50) ALDH1A1HSD17B10CYP3A4ALOX15CASP1
SCHEMBL29546125 0.85 HSD17B10 (0.50) ALDH1A1HSD17B10CYP3A4ALOX15CASP1
SCHEMBL140573 0.85 ALDH1A1 (0.65) ALDH1A1HSD17B10CYP3A4ALOX15CASP1
SCHEMBL28007756 0.85 ALDH1A1 (0.46) ALDH1A1HSD17B10CYP3A4ALOX15CASP1
SCHEMBL3793739 0.85 CYP3A4 (0.54) ALDH1A1HSD17B10CYP3A4ALOX15CASP1
SCHEMBL27715394 0.85 TSHR (0.56) ALDH1A1HSD17B10CYP3A4ALOX15CASP1
SCHEMBL1478478 0.83 ALDH1A1 (0.62) ALDH1A1HSD17B10CYP3A4ALOX15CASP1
Hydrochloric Acid SCHEMBL9312867 0.83 CYP3A4 (0.58) ALDH1A1HSD17B10CYP3A4ALOX15CASP1
SCHEMBL2936687 0.83 ALOX15 (0.54) ALDH1A1HSD17B10CYP3A4ALOX15CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024094962-A1 PYRIDO[2,3-D]PYRIMIDIN-2-AMINE DERIVATIVES AS EGFR INHIBITORS FOR THE TREATMENT OF CANCER CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2024-05-10 WO claimed
EP-3911629-A1 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS, PREPARATION AND USE THEREOF PI Industries Ltd. (IN) 2021-11-24 EP claimed
WO-2020148617-A1 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS, PREPARATION AND USE THEREOF PI INDUSTRIES LTD. (IN) 2020-07-23 WO claimed
CN-110191942-A Multi-functional olefin copolymer and lubricating composition containing it 雅富顿化学公司 2019-08-30 CN claimed
CN-109705956-A Enhance the dispersant viscosity index improvers of the abrasion protection of engine oil 雅富顿化学公司 2019-05-03 CN claimed
CN-103097360-B Process for preparing antiviral compounds ABBVIE INC. (BS) 2016-02-10 CN claimed
EP-1480605-A1 HAIR COLORING COMPOSITIONS BASED ON DIAMINOPYRAZOLE COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 2004-12-01 EP claimed
WO-2003075872-A1 HAIR COLORING COMPOSITIONS BASED ON DIAMINOPYRAZOLE COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 2003-09-18 WO claimed
CN-120463599-A Preparation method of 2, 6-diaminobiphenyl alkene 上海裕兰生物科技有限公司 2025-08-12 CN disclosed
CN-120463599-A Preparation method of 2, 6-diaminobiphenyl alkene 上海裕兰生物科技有限公司 2025-08-12 CN disclosed
WO-2025096710-A1 MODULATORS OF BCL6 AS LIGAND DIRECTED DEGRADERS BRISTOL-MYERS SQUIBB COMPANY (US) 2025-05-08 WO disclosed
WO-2024094962-A1 PYRIDO[2,3-D]PYRIMIDIN-2-AMINE DERIVATIVES AS EGFR INHIBITORS FOR THE TREATMENT OF CANCER CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2024-05-10 WO disclosed
WO-2023176172-A1 POLYIMIDE RESIN PRECURSOR 東京応化工業株式会社 2023-09-21 WO disclosed
CN-116096201-A Delayed fluorescence organic electroluminescent element, display device and lighting device 学校法人关西学院 2023-05-09 CN disclosed
EP-1000123-A2 USE OF REACTIVE DYES FOR DYEING HAIR BASF AKTIENGESELLSCHAFT (DE) 2000-05-17 EP disclosed
WO-1999005222-A2 USE OF REACTIVE DYES FOR DYEING HAIR BASF AKTIENGESELLSCHAFT (DE) 1999-02-04 WO disclosed
US-5475137-A Electrolgraphy; charge transfer compounds RICOH COMPANY, LTD. (JP) 1995-12-12 US disclosed
US-5436100-A A charge transport compound comprising a N-Ar-3-(diphenyl-amino)diphenylamine where Ar is a condensed or noncondensed polycyclic carbo ring; durability; heat resistance; mechanical shockproof RICOH COMPANY, LTD. (JP) 1995-07-25 US disclosed
US-5334470-A Resistant to heat and mechanical shocks RICOH COMPANY, LTD. (JP) 1994-08-02 US disclosed
US-4058529-A Polycyclic amino derivatives of pyrrolidone and piperidone CIBA-GEIGY CORPORATION (US) 1977-11-15 US disclosed