Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.44 |
| ▸ | MMP12 | P39900 | 1/20 | 0.44 |
| ▸ | RHEB | Q15382 | 2/20 | 0.39 |
| ▸ | KMO | O15229 | 1/20 | 0.36 |
| ▸ | FABP4 | P15090 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HRH2 | P25021 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1173483 | 0.89 | ALDH1A1 (0.42) | PRKCAMMP12L3MBTL1MAPTNCEH1 | |
| SCHEMBL13095926 | 0.88 | PRKCA (0.41) | PRKCAMMP12RHEBKMOFABP4 | |
| SCHEMBL5300454 | 0.85 | PRKCA (0.40) | PRKCAMMP12KMOFABP4L3MBTL1 | |
| SCHEMBL2907228 | 0.85 | PRKCA (0.50) | PRKCAMMP12KMOFABP4L3MBTL1 | |
| SCHEMBL5233882 | 0.85 | PRKCA (0.42) | PRKCAMMP12RHEBKMOFABP4 | |
| SCHEMBL5438990 | 0.83 | PRKCA (0.45) | PRKCAMMP12L3MBTL1MAPTEGLN1 | |
| SCHEMBL5443976 | 0.83 | PRKCA (0.45) | PRKCAMMP12RHEBKMOFABP4 | |
| SCHEMBL5440051 | 0.82 | PRKCA (0.44) | PRKCAMMP12SCN9A | |
| SCHEMBL5440954 | 0.82 | PRKCA (0.44) | PRKCAMMP12L3MBTL1MAPTSCN9A | |
| SCHEMBL5433925 | 0.82 | PRKCA (0.44) | PRKCAMMP12SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1613634-A1 | INDOLE ACETAMIDES AS INHIBITORS OF THE HEPATITIS C VIRUS NS5B POLYMERASE | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.P.A. (IT) | 2006-01-11 | — | — | EP | disclosed |
| WO-2004087714-A1 | INDOLE ACETAMIDES AS INHIBITORS OF THE HEPATITIS C VIRUS NS5B POLYMERASE | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P ANGELETTI SPA (IT) | 2004-10-14 | — | — | WO | disclosed |