Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 6/20 | 0.51 |
| ▸ | CTSS | P25774 | 5/20 | 0.51 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9318110 | 0.84 | CTSK (0.53) | CTSKCTSSGABRB1GABRB2MAPT | |
| SCHEMBL21243787 | 0.84 | CTSK (0.50) | CTSKCTSSGABRB1GABRB2MAPT | |
| SCHEMBL21243759 | 0.84 | CTSK (0.50) | CTSKCTSSGABRB1GABRB2MAPT | |
| SCHEMBL3288025 | 0.83 | SLC6A4 (0.54) | CTSKCTSSGABRB1GABRB2MAPT | |
| SCHEMBL13211540 | 0.83 | SLC6A4 (0.54) | CTSKCTSSGABRB1GABRB2MAPT | |
| SCHEMBL13232389 | 0.83 | SLC6A4 (0.54) | CTSKCTSSGABRB1GABRB2MAPT | |
| SCHEMBL22433704 | 0.83 | SLC6A4 (0.54) | CTSKCTSSGABRB1GABRB2MAPT | |
| SCHEMBL4441037 | 0.83 | SLC6A4 (0.54) | CTSKCTSSGABRB1GABRB2MAPT | |
| SCHEMBL18918278 | 0.83 | SLC6A4 (0.54) | CTSKCTSSGABRB1GABRB2MAPT | |
| SCHEMBL5471683 | 0.83 | CTSK (0.55) | CTSKCTSSGABRB1GABRB2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401821-A4 | NOVEL PHENYLALKYL DIAMINE AND AMIDE ANALOGS | SK CORP (KR) | 2006-05-31 | — | — | EP | disclosed |
| EP-1401821-A1 | NOVEL PHENYLALKYL DIAMINE AND AMIDE ANALOGS | SK Corporation (KR) | 2004-03-31 | — | — | EP | disclosed |
| WO-2002100848-A1 | NOVEL PHENYLALKYL DIAMINE AND AMIDE ANALOGS | SK CORPORATION (KR) | 2002-12-19 | — | — | WO | disclosed |