Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 5/20 | 0.53 |
| ▸ | CTSS | P25774 | 4/20 | 0.53 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3288025 | 0.86 | SLC6A4 (0.54) | CTSKCTSSGABRB1GABRB2MAPT | |
| SCHEMBL18918278 | 0.86 | SLC6A4 (0.54) | CTSKCTSSGABRB1GABRB2MAPT | |
| SCHEMBL22433704 | 0.86 | SLC6A4 (0.54) | CTSKCTSSGABRB1GABRB2MAPT | |
| SCHEMBL13211540 | 0.86 | SLC6A4 (0.54) | CTSKCTSSGABRB1GABRB2MAPT | |
| SCHEMBL13232389 | 0.86 | SLC6A4 (0.54) | CTSKCTSSGABRB1GABRB2MAPT | |
| SCHEMBL4441037 | 0.86 | SLC6A4 (0.54) | CTSKCTSSGABRB1GABRB2MAPT | |
| SCHEMBL15632169 | 0.84 | CTSK (0.51) | CTSKCTSSGABRB1GABRB2MAPT | |
| SCHEMBL5755881 | 0.84 | CTSK (0.51) | CTSKCTSSGABRB1GABRB2MAPT | |
| SCHEMBL14923545 | 0.84 | CTSK (0.51) | CTSKCTSSGABRB1GABRB2MAPT | |
| SCHEMBL15632507 | 0.84 | CTSK (0.51) | CTSKCTSSGABRB1GABRB2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116547275-A | IL-17A modulators | 赛诺菲 | 2023-08-04 | — | — | CN | disclosed |
| EP-0593557-A1 | AROMATIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE IN THERAPY. | MERCK SHARP & DOHME (GB) | 1994-04-27 | — | — | EP | disclosed |