Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 3/20 | 0.51 |
| ▸ | GRM5 | P41594 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 6/20 | 0.41 |
| ▸ | EDNRA | P25101 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 3/20 | 0.40 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CD69 | Q07108 | 1/20 | 0.37 |
| ▸ | EDNRB | P24530 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL751446 | 0.98 | GRM1 (0.50) | GRM1GRM5ALDH1A1GAABCHE | |
| SCHEMBL6324783 | 0.87 | ALDH1A1 (0.42) | GRM1GRM5ALDH1A1GAAEDNRA | |
| SCHEMBL8813838 | 0.85 | BCHE (0.46) | GRM1GRM5BCHEACHENOX1 | |
| SCHEMBL27503672 | 0.84 | GRM1 (0.45) | GRM1GRM5ALDH1A1GAABCHE | |
| SCHEMBL8814780 | 0.84 | GRM1 (0.43) | GRM1GRM5ALDH1A1GAABCHE | |
| SCHEMBL11823616 | 0.83 | GRM1 (0.45) | GRM1GRM5ALDH1A1GAABCHE | |
| SCHEMBL6970747 | 0.83 | GRM1 (0.42) | GRM1GRM5ALDH1A1GAABCHE | |
| SCHEMBL8817077 | 0.82 | GRM1 (0.40) | GRM1GRM5ALDH1A1GAANOX1 | |
| SCHEMBL10355854 | 0.81 | EDNRA (0.50) | ALDH1A1EDNRAMEN1LMNAKMT2A | |
| SCHEMBL11527593 | 0.81 | EDNRA (0.50) | ALDH1A1EDNRAMEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1303499-B1 | TETRAZOLE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2006-07-12 | — | — | EP | claimed |
| EP-1303499-A1 | TETRAZOLE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-04-23 | — | — | EP | claimed |
| US-6399641-B1 | FOR THERAPY AND PROPHYLAXIS OF PSYCHOSIS, SCHIZOPHRENIA, ALZHEIMER'S DISEASE, COGNITIVE DISORDERS AND RESTRICTED BRAIN FUNCTION CAUSED BY BYPASS OPERATIONS OR TRANSPLANTS, POOR BLOOD SUPPLY TO THE BRAIN, SPINAL CORD INJURIES ETC. | HOFFMANN-LA ROCHE INC. | 2002-06-04 | — | — | US | claimed |
| US-20020022648-A1 | Novel 2H-tetrazole-amide compounds with therapeutic activity as metabotropic glutamate receptor agonists | HOFFMANN-LA ROCHE INC. | 2002-02-21 | — | — | US | claimed |
| WO-2002006254-A1 | TETRAZOLE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-01-24 | — | — | WO | claimed |
| EP-3947351-B1 | SMALL MOLECULE PARG INHIBITORS AND METHODS OF USE THEREOF | UNIV TEXAS (US) | 2026-03-11 | — | — | EP | disclosed |
| US-12491188-B2 | Small molecule PARG inhibitors and methods of use thereof | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2025-12-09 | — | — | US | disclosed |
| US-20220202821-A1 | SMALL MOLECULE PARG INHIBITORS AND METHODS OF USE THEREOF | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2022-06-30 | — | — | US | disclosed |
| EP-3947351-A2 | SMALL MOLECULE PARG INHIBITORS AND METHODS OF USE THEREOF | Board of Regents, The University of Texas System (US) | 2022-02-09 | — | — | EP | disclosed |
| WO-2020205646-A2 | SMALL MOLECULE PARG INHIBITORS AND METHODS OF USE THEREOF | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2020-10-08 | — | — | WO | disclosed |
| US-10683275-B2 | Leveler, leveler composition and method for electrodeposition of metals in microelectronics | Shinhao Materials LLC (CN) | 2020-06-16 | — | — | US | disclosed |
| US-20190263773-A1 | LEVELER, LEVELER COMPOSITION AND METHOD FOR ELECTRODEPOSITION OF METALS IN MICROELECTRONICS | Shinhao Materials LLC (CN) | 2019-08-29 | — | — | US | disclosed |
| US-5922558-A | REACTING A PEROXIDASE ENZYME WITH A PEROXIDE AND AT LEAST ONE NOVEL COMPOUND HAVING AN ELECTRON RICH C-C DOUBLE BOND REACTIVE TO PEROXIDASE AND THE PEROXIDE TO PRODUCE AN EXCITED STATE COMPOUND; ALSO USEFUL IN ASSAYS FOR PEROXIDASE ENZYMES | LUMIGEN, INC. (US) | 1999-07-13 | — | — | US | disclosed |
| EP-0916668-A1 | CHEMOKINE RECEPTOR ANTAGONISTS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-05-19 | — | — | EP | disclosed |
| WO-1999014358-A1 | CHEMILUMINESCENCE COMPOSITIONS AND METHODS | LUMIGEN, INC. (US) | 1999-03-25 | — | — | WO | disclosed |
| WO-1999014220-A1 | NOVEL COMPOUNDS FOR GENERATING CHEMILUMINESCENCE WITH A PEROXIDASE | LUMIGEN, INC. (US) | 1999-03-25 | — | — | WO | disclosed |
| WO-1997006178-A1 | PYRIMIDINE NUCLEOSIDES | F. HOFFMANN-LA ROCHE AG (CH) | 1997-02-20 | — | — | WO | disclosed |
| US-5258260-A | Aqueous developable deep UV negative resist | OLIN CORPORATION (US) | 1993-11-02 | — | — | US | disclosed |
| US-5258265-A | Aqueous developable deep UV negative resist | OLIN CORPORATION (US) | 1993-11-02 | — | — | US | disclosed |
| US-5178987-A | Aqueous developable deep UV negative resist containing benzannelated acetic acid and novolak resin | OLIN CORPORATION (US) | 1993-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10683275-B2 | Leveler, leveler composition and method for electrodeposition of metals in microelectronics | KCNN4, MB, KCNN2 | GRM1 942/4885GRM5 1131/4885ALDH1A1 563/4885 |
| US-12491188-B2 | Small molecule PARG inhibitors and methods of use thereof | PARG, PARP15, PLG | GRM1 3972/4885GRM5 1047/4885ALDH1A1 4146/4885 |
| US-20220202821-A1 | SMALL MOLECULE PARG INHIBITORS AND METHODS OF USE THEREOF | PARG, PARP15, PLG | GRM1 3972/4885GRM5 1047/4885ALDH1A1 4146/4885 |
| US-20190263773-A1 | LEVELER, LEVELER COMPOSITION AND METHOD FOR ELECTRODEPOSITION OF METALS IN MICROELECTRONICS | KCNN4, MB, KCNN2 | GRM1 942/4885GRM5 1131/4885ALDH1A1 563/4885 |
| US-20020022648-A1 | Novel 2H-tetrazole-amide compounds with therapeutic activity as metabotropic glutamate receptor agonists | GRM1, GRM3, GRM2 | GRM1 1/4885GRM5 4/4885ALDH1A1 2423/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.