Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 2/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MYLK | Q15746 | 2/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5756547 | 0.84 | GRM1 (0.51) | GRM1GRM5ALDH1A1GAABCHE | |
| SCHEMBL751446 | 0.82 | GRM1 (0.50) | GRM1GRM5ALDH1A1GAABCHE | |
| SCHEMBL8817077 | 0.82 | GRM1 (0.40) | GRM1GRM5ALDH1A1GAAGPR84 | |
| SCHEMBL8813838 | 0.78 | BCHE (0.46) | GRM1GRM5MAPTHPGDMAPK1 | |
| SCHEMBL6324783 | 0.76 | ALDH1A1 (0.42) | GRM1GRM5ALDH1A1MAPTHPGD | |
| SCHEMBL6970747 | 0.72 | GRM1 (0.42) | GRM1GRM5ALDH1A1MAPTHPGD | |
| SCHEMBL10355854 | 0.71 | EDNRA (0.50) | ALDH1A1NPSR1TSHRLMNA | |
| SCHEMBL11527593 | 0.71 | EDNRA (0.50) | ALDH1A1NPSR1TSHRLMNA | |
| SCHEMBL6432188 | 0.71 | GRM1 (0.46) | GRM1GRM5ALDH1A1GAABCHE | |
| SCHEMBL8816019 | 0.70 | CRHBP (0.39) | ALDH1A1CRHBPCRHR2TSHRAKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997006178-A1 | PYRIMIDINE NUCLEOSIDES | F. HOFFMANN-LA ROCHE AG (CH) | 1997-02-20 | — | — | WO | disclosed |