Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 9/20 | 0.36 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.31 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | BCL2 | P10415 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.31 |
| ▸ | MC4R | P32245 | 1/20 | 0.30 |
| ▸ | MC5R | P33032 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5754912 | 0.91 | CACNA1B (0.43) | CACNA1BHSD17B10ATMALDH1A1MEN1 | |
| SCHEMBL5758645 | 0.91 | CACNA1B (0.43) | CACNA1BHSD17B10ATMALDH1A1MEN1 | |
| SCHEMBL5755568 | 0.90 | CACNA1B (0.35) | CACNA1BHTRA1ALDH1A1L3MBTL1FKBP4 | |
| SCHEMBL5759035 | 0.90 | CACNA1B (0.49) | CACNA1BHSD17B10ATMMCL1MEN1 | |
| SCHEMBL5754736 | 0.90 | CACNA1B (0.40) | CACNA1BHSD17B10ATML3MBTL1MEN1 | |
| SCHEMBL5758199 | 0.88 | CACNA1B (0.43) | CACNA1BHSD17B10ATMMCL1BCL2 | |
| SCHEMBL5759489 | 0.88 | MCL1 (0.34) | MCL1HTRA1ALDH1A1ITGA4ITGB7 | |
| SCHEMBL5755981 | 0.86 | KMT2A (0.38) | CACNA1BHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL5757036 | 0.85 | CACNA1B (0.45) | CACNA1BHSD17B10ALDH1A1KMT2A | |
| SCHEMBL5754795 | 0.85 | CACNA1B (0.43) | CACNA1BHSD17B10ATMMCL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0997147-B1 | AMINO ACID DERIVATIVES | ONO PHARMACEUTICAL CO (JP) | 2006-03-15 | — | — | EP | claimed |